ea0010p63 | Reproduction | SFE2005
Chattopadhyay A
, Al-Othman A
, Bayoumy H
, Moharib N
, Nazmi N
, Al-Alwadi Q
The development of Leydig cells and steroidogenesis are controlled by activation of luteinizing hormone (LH) receptors by placental HCG during intrauterine life and by pituitary LH after birth. Naturally occurring isolated LH deficiency in man thus provide useful information to understand the intriguing role of this gonadotrophin.The patient was a 23 yr-old man from Afghanistan with a 46, XY karyotype. He presented with absent pubertal development and pr...