Searchable abstracts of presentations at key conferences in endocrinology

ea0035p20 | Adrenal cortex | ECE2014

Measurement of serum total cortisol using HPLC coupled ESI–TOF mass spectrometry

Tarjanyi Zita , Montsko Gergely , Mezosi Emese , Kovacs Gabor L

Cortisol is a glucocorticoid hormone with low molecular weight (362 Da) synthesized from cholesterol in the adrenal gland. The release is regulated by the hypothalamic–pituitary-adrenal (HPA) axis. Approximately 95% of the circulating amount is bound to proteins (CBG and albumin), but only the remaining free fraction is biologically active. Serum cortisol level is routinely analysed in laboratory medicine, though the widespread immunoassays (RIA and ECLIA) have the disadv...

ea0063gp169 | Obesity (1) | ECE2019

The role of copeptin and cortisol in critically ill patients

Gergics Marin , Pham-Dobor Greta , Tarjanyi Zita , Montsko Gergely , Kőszegi Tamas , Mezősi Emese , Bajnok Laszlo

Introduction: Both cortisol and vasopressin are stress hormones. Earlier, our group demonstrated that serum concentrations of free cortisol at admissions to the Intensive Care Unit (ICU) were independent predictors of survival in critically ill patients. Other investigators have demonstrated that serum copeptin, a surrogate marker of vasopressin may also be a predictive factor in this patient population. The aim of our present study was to compare the prognostic roles of serum...