Endocrine Abstracts

A 55-year-old man known primary hypoparathyroidism, presented with recurrent episodes of collapses. Past Medical history of CVA, Recurrent episodes of collapse, Secondary Polycythaemia. His S Calcium ranges from 1.5 to 1.7. Not always symptomatic. Occasionally, c/o pins and needles. But having recurrent episodes of collapses with loss of consciousness. Each Episode lasts for 10 to 15 seconds. This is going on for more than 15 years. In 2013 his Calcitriol supplement was increa...

A 54 year old male was referred by GP for abnormal TFT. Thyroid function was done routinely. TSH 3.0 (normal 0.5 to 4.5), FT4-25.2. GP repeated the TFT twice, and both of them were similar. There were no clinical features of Thyrotoxicosis. On examination, his heart rate was 78/min regular, wt 79 kg, no thyroid enlargement, no tremor. Cardiovascular examination was unremarkable. He is fit and well gentleman. He does not take any regular medication. No history of taking any oth...

This is 66 year old lady was referred by GP for Abnormal TFT. Her TFT was done routinely and showed TSH-2.7, FT4-9.8. Patient did not have symptoms of hypothyroidism, or did not have any weight gain. On examination, thyroid was not enlarged. In view of Low FT4, she was started on Levothyroxine 25 mcg once daily. After taking the medications she felt warm and unsteady and noticed tremour on both hands. The repeat TFT came back as normal. TSH-2.9, FT4-14.2\. In view of pts sympt...

This was a 26 year old girl was referred for addisons disease. Her initial blood test showed low Na-123 with raised K-6. She complained feeling tired and lethargic for last 2 months. On examination, wt 108 kg, alopecia on the occipital scalp. Obese lady, CVS and respiratory system examination were normal. Her Short Synacthen test showed blunted response. She was immediately started on Hydrocortisone 10-5-5. Furhter bloods showed TSH-18, FT4-5.6, positive Anti TPO Ab, positive ...

This is a 46 year old man who was referred by GP for erectile dysfunction. He is a married with two daughters. His complaint started 1 year back with lethargy and tiredness. He is fit and well. He does not take any regular medication. He is shaving regularly. On examination, wt 80 kg. All the secondary sexual characteristics were present. No Galactorrohoea. Testes size was normal. His total testosterone level was low. Anterior pituitary hormone profile showed very low LH and F...

A 29 year-old nursing student, was incidentally detected to have high serum calcium 3.43 mmol/l (2.2-2.6) whilst being treated for community acquired pneumonia. She had no symptoms of hypercalcaemia. Her uncle had been operated for primary hyperparathyroidism (PHPT) although only limited details were available. PTH of 28 pmol/l (1.6-7.2) confirmed the diagnosis of PHPT. She had vitamin D deficiency, normal liver and renal function. She was offered parathyroidectomy and preoper...

Summary: A case of intermittent hypercalcemia with a suppressed parathyroid hormone (PTH) for nearly 3 years. It was found that high calcium specifically occurred in summer and each one lasted for about a month. Once calcium normalised the renal function also improved. Exact aetiology has not been found even after extensive investigations.Case presentation: A 67-year-old gentleman first presented to the endocrine clinic in early 2014 with Hypercalcemia. ...

Aim: Hyperthyroidism can affect pregnancy outcomes based on activity of the disease, ongoing use of anti-thyroid drugs (ATD) and TSH receptor antibody (TRAB) positivity. The aim of our audit was to analyse the outcomes of fetal monitoring in pregnant women with previous or current history of active hyperthyroidismMethods: The data on all patients with hyperthyroidism and pregnancy over 3 years was collected. The local guidelines recommend TRAB check at 2...