Searchable abstracts of presentations at key conferences in endocrinology

ea0004dp26 | Diabetes, metabolism and cardiovascular | SFE2002

Diol-ginsenosides delayed the onset of diabetes possibly by the increase in beta-cell resistance in DP-BB rats

Moon C , Ju C , Kim M , Chae S , Kim G , Chung A

The present study was designed to investigate the effects of Diol-ginsenosides, major active components of Panax Ginseng, on the development of diabetes in the Diabetes Prone-BB rats(DP-BB rats). Administration of Diol-ginsenosides to DP-BB rats from age 3-4 weeks to age 11-12 weeks (daily, 1mg/g body weight) resulted in a markedly delayed the onset of diabetes. Islets of the treated rats showed no insulitis or only early/intermediate-stage insulitis and preserved higher pancr...