Endocrine Abstracts

Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorder of women at reproductive-age and accounts for 80% of the causes of anovulatory infertility. Despite the widely characterized reproductive, endocrine, and metabolic abnormalities, the mechanisms underlying PCOS remain unclear. Thus, it is essential to identify novel biomarkers that will allow to disclosure novel pathways involved PCOS pathophysiology, which could then be used to improve PCOS manage...

Infertility is a global health problem that affects about 15% of couples and approximately half of infertility cases are associated with male factors. Oxidative Stress (OS) is reported as one of the major causes of male infertility, mainly due to spermatozoa’s vulnerability to the attack of reactive oxygen species (ROS). Infertile couples often recur to assisted reproductive technology (ART) to achieve a successful pregnancy. However, ART protocols also increase the expos...