Searchable abstracts of presentations at key conferences in endocrinology

ea0035p571 | Endocrine tumours and neoplasia | ECE2014

Androgens regulate gene expression of glucose transporters and glycolytic enzymes in prostate cancer cells

Vaz Catia V , Alves Marco G , Marques Ricardo , Moreira Paula I , Oliveira Pedro F , Cavaco Jose E , Maia Claudio J , Socorro Silvia

Prostate cancer (PCa) is an endocrine tumor that presents distinct metabolic features associated with neoplastic development, namely in the transition from the androgen-dependent to the androgen-independent phenotype that characterizes advanced stages of prostate cancer. Recently, we have found that LNCaP (androgen-responsive) and PC3 (androgen-nonresponsive) PCa cells present distinct glycolytic metabolism profiles in consequence of altered gene expression and/or activity of ...