Searchable abstracts of presentations at key conferences in endocrinology

ea0039oc6.10 | Oral Communications 6 | BSPED2015

Neuroradiological features in a cohort of 53 children with Thickened Pituitary Stalk (TPS) and/or idiopathic central diabetes insipidus

Cerbone Manuela , Ederies Ash , Losa Laura , Moreno Carolina , Spoudeas Helen A

Introduction: Children with TPS and/or ICDI represent a diagnostic and management conundrum. Agreed radiological criteria for TPS are lacking.Aims: To longitudinally characterize the neuroradiological features of children presenting with TPS and/or ICDI due to different aetiologies (oncological, inflammatory, idiopathic).Methods: We searched the terms ‘thickened pituitary stalk’ or ‘idiopathic diabetes insipidus&#146...

ea0073ep8 | Adrenal and Cardiovascular Endocrinology | ECE2021

Very large adrenal nodule and Cushing syndrome – when histology differs from the clinical suspicion

Lavrador Mariana , Moreno Carolina , Luísa Barros , Paiva Isabel

IntroductionThe malignancy risk of an adrenal nodule is based on clinical symptoms (rapid onset of hypercortisolism and hyperandrogenism; mass symptoms) and imaging characteristics. These suspicious criteria include boundary irregularities, heterogeneity, dimension>6 cm and density>20 HU (CT). However, these are not absolute criteria.Case reportWe report the case of a 43 years-old female patient with a histor...

ea0081ep62 | Adrenal and Cardiovascular Endocrinology | ECE2022

Synchronous adrenal gland masses in a patient: clinical case

Ferreira Mafalda Martins , Lavrador Mariana , Araujo Catia , Guiomar Joana Reis , Moreno Carolina , Oliveira Patricia , Paiva Isabel

We describe the case of a 69-year-old woman with bilateral adrenal incidentalomas identified in CT-scan: on the right, a 57 mm heterogeneous mass with <10 Hounsfield units(HU) with absolute washout of 16%; on the left a 13 mm mass with 35UH, intense contrast enhancement but washout of 66%. She had a recent onset of diabetes, hypertension, androgenic alopecia and facial hair. The systolic blood pressure remained persistently >160 mmHg despite receiving four antihyperten...

ea0081ep63 | Adrenal and Cardiovascular Endocrinology | ECE2022

Malignant pheochromocytoma with bone, pulmonary and brain metastases

Araujo Catia , Ferreira Mafalda Martins , Lavrador Mariana , Moreno Carolina , Oliveira Patricia , Baptista Carla , Paiva Isabel

Introduction: Pheochromocytomas are rare neuroendocrine tumors whose malignancy is defined by the presence of metastases that may appear several years later. The appropriate follow-up time remains uncertain.Clinical Case: We present the case of a woman with a history of pheochromocytoma who underwent complete resection at 48 years old. The genetic evaluation was negative for mutations on RET, VHL, SDHB or SDHD genes. At 66 years old, a thoracic vertebral...

ea0036P77 | (1) | BSPED2014

Thickened pituitary stalk (TPS) and/or idiopathic central diabetes insipidus (ICDI): a single centre experience of occult causative pathology evolving in 54 children over 30 years

Cerbone Manuela , Ederies Ash , Losa Laura , Moreno Carolina , Sun Kristi , Spoudeas Helen A

Introduction: Thickened pituitary stalk (TPS) and/or idiopathic central diabetes insipidus (ICDI) are rare in childhood, presenting to different (endocrine, oncology, ophthalmology) specialties. In the absence of other diagnostic features, agreed radiological definitions, biopsy (often too dangerous) or consensus management guidance, subsequent surveillance and treatment are uncertain. Cases may remain undiagnosed or evolve over decades.Aims: i) To longi...

ea0035p328 | Clinical case reports Thyroid/Others | ECE2014

Gynecomastia: a rare etiology

Vicente Nuno , Barros Luisa , Saraiva Joana , Moreno Carolina , Guelho Daniela , Cardoso Luis , Carrilho Francisco

Introduction: Gynecomastia is a frequent reason for endocrinology consultation and its correct investigation is pivotal towards a precise diagnosis. We present a clinical case of a rare cause of gynecomastia.Case report: A 56-year-old male was referred to the hospital setting for an endocrinology consultation. He noticed increased breast size for a year, initially tender to palpation, and unquantified weight loss. Neither galactorrhea, nor any nipple dis...

ea0035p609 | Endocrine tumours and neoplasia | ECE2014

Adrenocortical carcinomas: retrospective analysis of the last 22 years

Guelho Daniela , Paiva Isabel , Vieira Alexandra , Saraiva Joana , Moreno Carolina , Vicente Nuno , Cardoso Luis , Carrilho Francisco

Introduction: Adrenocortical carcinoma (ACC) is a rare disease, with a severely adverse prognosis. Clinical reports, even when including a limited number of cases, can contribute to its knowledge. This study aims to characterize patients followed at our department between 1991 and 2013.Methods: Retrospective analysis of the clinical records of patients with pathological confirmation of ACC. Statistical analysis: SPSS21.Results: 22 ...

ea0035p944 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Weight and metabolic profile evolution in patients with treated prolatinomas

Guelho Daniela , Gomes Leonor , Paiva Isabel , Saraiva Joana , Moreno Carolina , Cardoso Luis , Vicente Nuno , Carrilho Francisco

Introduction: The metabolic consequences of hyperprolactinemia and the repercussions of its treatment with dopaminergic agonists are not yet fully understood. This study aims to evaluate the metabolic profile of patients with prolactinomas (prevalence of diabetes mellitus, dyslipidaemia and obesity) and identify the potential variations after treatment with bromocriptine.Methods: Retrospective study of patients followed between 1962 and 2013. Included 17...

ea0032p40 | Adrenal cortex | ECE2013

Autoimmune polyglandular syndrome on a cohort of patients with primary adrenocortical insufficiency

Gouveia Sofia , Ribeiro Cristina , Alves Marcia , Saraiva Joana , Moreno Carolina , Guelho Daniela , Carrilho Francisco

Introduction: On average, 40 to 50% of the patients with autoimmune adrenocortical insufficiency will eventually develop an autoimmune polyglandular syndrome (APS). Our aim was to characterize a population with primary adrenocortical insufficiency (AI) and determine the prevalence of other autoimmune disorders that might establish the diagnosis of APS.Materials and methods: We included patients with primary AI under surveillance at our Department. Those ...

ea0032p355 | Diabetes | ECE2013

Predictive value of HbA1c and glucose fluctuations in hypoglycemia risk in patients with type 1 diabetes

Guelho Daniela , Barros Luisa , Baptista Carla , Paiva Isabel , Gouveis Sofia , Saraiva Joana , Moreno Carolina , Carrilho Francisco

Introduction: Many patients with diabetes experience high variability in glucose concentrations which is associated with a risk of hypoglycemia. The aim of this was to compare the predictive value of HbA1C, mean interstitial glucose (MIG), and glucose variability (GV) in the risk of hypoglycemia in patients with type 1 diabetes (T1D).Methods: Continuous glucose monitoring, using CGMS system, was performed in 130 T1D patients with diabetes duration of 17....