Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep474 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Debut diabetes characteristics

Exposito Maria Rosa Alhambra , Sanchez Inmaculada Prior , Moreno Paloma Moreno , Moreno Maria Angeles Galvez

Background: The diabetes type 1 (DM1) is a chronic autoimmune disease, it tends to appear in childhood, its incidence continues to rise and the complications arising from improper care poses serious health problems for those who suffer. LADA diabetes is autoimmune diabetes which appear in adults.Objetive: To describe the characteristics of the new diabetes debut in our environment.Material and methods: We included all patients who ...

ea0049ep602 | Diabetes therapy | ECE2017

Real practice experience: Degludec vs Glargina U300

Exposito Maria Rosa Alhambra , Sanchez Inmaculada Prior , Moreno Paloma Moreno , Moreno M Angeles Galvez

Background: In last year, different analogues of very long duration basal insulin have appeared, which favors the flexibility in its use. Both ensure a decrease in the rate of hypoglycemia and improve glycemic control in clinical trials. However, in real practice we have few data in real practice.Objective: To compare the two ultralente insulin analogues in real practice. To analyze if they are cost effective.Material and methods: ...

ea0041ep753 | Neuroendocrinology | ECE2016

Prognostic factors of pituitary growth hormone-secreting tumors

Alhambra Exposito Maria Rosa , Ibanez Costa Alejandro , Moreno Paloma Moreno , Galvez Moreno Maria Angeles

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. Transphenoidal surgery is the first-choice treatment; however, the development of new drug therapies in the last years, specially the somatostatin analogues (SSA), has open new and promising avenues for the treatment of pituitary tumors.Objective: To determine whether a detailed knowledge of the clinico-pathological and radiologi...

ea0035p716 | Neuroendocrinology | ECE2014

Long-term remission and recurrence rates after transsphenoidal surgery for cushing's disease

Moreno Paloma Moreno , Fernandez Julia Silva , Exposito Maria Rosa Alhambra , Moreno Maria angeles Galvez

Objective: Transsphenoidal surgery (TSS) presents the treatment of choice for CushingÂ’s disease (CD), 95% microadenomas. Remission and recurrence rates vary dependent on tumor size, extension, adenoma visibility on magnetic resonance imaging, and neurosurgical expertise. Remission rates in the postoperative vary between 55 and 85%, with a recurrence of up to 25%. The aim of this study was to describe the rate of remission and recurrence of CD in our midst after TSS, and c...

ea0081ep113 | Adrenal and Cardiovascular Endocrinology | ECE2022

Adrenal venous sampling in patients with hyperaldosteronism

Rebollo-Roman Angel , Serrano Laguna Ma del Carmen , Perez-Montilla Maria-Eugenia , Moreno-Moreno Paloma , Moreno Maria Angeles Galvez

Objective: Adrenal venous sampling (AVP) is a reliable procedure to differentiate if in patients with primary aldosteronism (PA) aldosterone production is unilateral or bilateral and guide the treatment of these patients. Our objective was to describe their characteristics and the outcomes of the AVPs.Methods and patients: Observational longitudinal clinical study between July 2020 and September 2021 in patients who underwent AVP in our Hospital.<p c...

ea0049ep882 | Growth hormone IGF axis - basic | ECE2017

Could statin modify molecular phenotype of pituitary growth hormone-secreting tumors?

Exposito Maria Rosa Alhambra , Moreno Paloma Moreno , Jimenez Concepcion Munoz , Moreno Maria Angeles Galvez , Huertas Raul Luque

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. In the last years, statins have been implicated in the response to treatment of patients with acromegaly. Although this fact is not very clear.Objective: To analyze whether pretreatment with statins modifies the adenoma molecular phenotype of the acromegalic patients and how this changes could help to influence the response to tr...

ea0032p521 | Endocrine tumours and neoplasia | ECE2013

Diagnosis of endogenous hyperinsulinism through arterial calcium stimulation with hepatic venous sampling

Moreno Paloma Moreno , Exposito Maria Rosa Alhambra , Tendero Luis Zurera , Ortega Rafael Palomares , Moreno Maria Angeles Galvez , Lopez Pedro Benito

Objective: The aim of this study was to assess the utility of arterial calcium stimulation with hepatic venous sampling (ASVS) in the localization of tumors in patients with endogenous hyperinsulinism not detected with other methods.Patients and methods: We performed a retrospective study of 30 patients admitted to our hospital for hypoglycemia who underwent ASVS because the source of hyperinsulinism was not clearly identified by other imaging techniques...

ea0056p487 | Diabetes therapy | ECE2018

Second setp in type 2 diabetes, what to choose?

Exposito Maria Rosa Alhambra , Moreno Paloma Moreno , Martin Ana Barrera , Sanchez Inmaculada Prior , Moreno Maria Angeles Galvez

Introduction: In type 2 diabetes the choice of the second drug after metformina is marked by the basic characteristics of the patient.Objetive: To analyze in real clinical practice the effectiveness of different antidiabetics.Material and methods: Observational study including patients with type 2 diabetes, in which we added to metformina different antidiabetics. We revised them 3-6 months from change.Results...

ea0063gp34 | Diabetes and Cardiovascular Disease | ECE2019

Stroke in diabetic patients and cardiovascular risk factors control

Idougourram Soraya Leon , Martin Ana Barrera , Roman Angel Rebollo , Moreno Paloma Moreno , Laguna Maria Alcantara , Ortega Rafael Palomares , Moreno Maria Angeles Galvez

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...

ea0032p970 | Steroid metabolism and action | ECE2013

Screening for Cushing’s syndrome in obese patients

Exposito Maria Rosa Alhambra , Jimenez Carmen Tenorio , Sanchez Inmaculada Prior , Puerta Maria Jose Molina , Moreno Paloma Moreno , Jimenez Concepcion Munoz , Moreno Maria Angeles Galvez , Lopez Pedro Benito

Background: CushingÂ’s syndrome (CS) is considered to be more frequent among patients with metabolic syndrome. Previous studies have suggested to perform a routine screening for CS in obese patients; however, more recent reports only recommend a case-finding approach in patients with uncontrolled diabetes and hypertension, despite appropriate treatment.Objective: The aim of this study was to evaluate the prevalence of unsuspected CS in morbidly obese...