Endocrine Abstracts

Insulin antibodies were common when animal insulin was used given its high immunogenicity. The advent of recombinant DNA technology in insulin production has reduced the incidence of insulin antibodies and its presence is rarely considered clinically significant. Exogenous Insulin Antibody Syndrome (EIAS) describes the formation of insulin antibodies to exogenous insulin. We present a case of a 65-year-old gentleman who was diagnosed with diabetes mellitus secondary to pancrea...

Patients with adrenal insufficiency should be prescribed stress dose steroids in acute settings to avoid adrenal crisis. Adrenal crisis is life-threatening if not recognized and if treatment is delayed. This audit aimed to identify the current practice of sick-day rule management in University Hospital Limerick of admitted patients with adrenal insufficiency. A cross-sectional analysis was conducted on inpatients referred for endocrinology consultation for adrenal insufficienc...

Diabetic Ketoacidosis (DKA) is a life threatening emergency and its management is frequently protocolised. Adherence to protocols has been shown to shorten the time to DKA resolution however the management recommendations outlined in most DKA protocols is based on weak evidence and/or consensus. The aim of this study was to evaluate the frequency with which divergence from local DKA protocol was observed at our institution. A retrospective review of medical records was conduct...