ea0039p4 | (1) | BSPED2015
Shah Pratik
, Rahman Sofia
, McElroy Sharon
, Gilbert Clare
, Morgan Kate
, Hinchey Louise
, Button Roberta
, Margetts Rebecca
, Senniappan Senthil
, Guemes Maria
, Levy Hannah
, Morte Marti Carles
, Celma Lezcano Carles
, Amin Rakesh
, Hussain Khalid
Background: CHI is a cause of severe hypoglycaemia in children. Diazoxide (KATP channel agonist) is used as first-line treatment but is known to cause severe hypertrichosis and reduced appetite in children. Diazoxide unresponsive CHI us treated with daily octreotide subcutaneous injections (34 times/day).Objective and hypotheses: To evaluate the efficacy, safety and pharmacokinetics of long acting Somatostatin analogue (Lanreotide) thera...