Searchable abstracts of presentations at key conferences in endocrinology

ea0085p28 | Gonadal, DSD and Reproduction | BSPED2022

Extreme overgrowth resulting from exposure to exogenous testosterone gel in a young boy

Hulse Tony , Munn Wendy

Background: Pseudo precocious puberty in young children usually arises from adrenal or less commonly testicular causes. Though rare, the possibility of an exogenous source should also be considered.Case Report: A 2 year 2 month old male child presented with apparent overgrowth since about 1 year of age. His height was 108 cms [+6.29 SDs], weight 21 kgs [+4.54 SDs] and head circumference 52.2 cms [2.76 SDs]. He looked very mature for his age but had no dy...

ea0085oc7.4 | Oral Communications 7 | BSPED2022

Type A insulin resistance syndrome presenting with PCOS features and an unusual pattern of diabetes in a 10-year-old female

Nath Susmita , Munn Wendy , Hulse Tony

Background: Type A insulin resistance syndrome (TAIRS) is rare (prevalence 1/100 000) and is caused by pathological mutations in the insulin receptor (INSR) gene. The clinical features tend to affect females more severely. Patients can present with severe hyperinsulinemia, hyperandrogenism and acanthosis nigricans. We report a case of a girl with symptoms initially suggestive of polycystic ovarian syndrome (PCOS) but also with asymptomatic diabetes mellitus.<p class="abste...