ea0029p1305 | Paediatric endocrinology | ICEECE2012
Wawrusiewicz-Kurylonek N.
, Bossowski A.
, Kretowski A.
, Sawicka B.
, Borysewicz-Sanczyk H.
, Piertewicz E.
, Szalecki M.
, Wikiera B.
, Barg E.
, Mysliwiec M.
, Kucharska A.
, Hilczer M.
, Goscik J.
, Gorska M.
Introduction: FOXP3 is a critical determinant of T regulatory cells (Tregs) development and function. Treg cells play a crucial role in modulating potentially self-reactive clones, and dysfunction of this cell type contributes to autoimmune disease such as Graves disease (GD) and Hashimotos thyroiditis (HT). The aim of our study was to estimate the association of three polymorphism of FOXP3 gene with the predisposition to GD and HT in Polish population.<p class...