Endocrine Abstracts

Objective: The objective of our study is to describe the lipid parameters of pregnant women with diabetes during the three trimesters of pregnancy.Materials and methods: This is a retrospective study that looked at 44 diabetic pregnant women. Clinical biological data were collected from medical records. The personal history of dyslipidemia, pathologies, and medications that may interfere with lipid parameters have been eliminated.R...

Introduction: Congenital combined pituitary hormone deficiency (CCPHD) is a rare disorder characterized by an impaired production of two or more hormones of the anterior pituitary gland. It is linked to different genetic mutations and requires an early diagnosis to prevent burdensome developmental consequences. Primary ovarian insufficiency, disparately is the depletion of ovarian function with loss of functional primordial follicles before the age of 40 years due to multiple ...

Introduction: The occurrence of Cushing’s syndrome in individuals with chronic renal failure is notably rare. It represents a challenging diagnosis in the context of pre-existing chronic kidney disease due to commonly associated alterations in the hypothalamic–pituitary–adrenal axis function. Consequently, the interpretation of standard tests used to detect hypercortisolism can be peculiarly difficult and reveal concrete particularities in comparison to patients...

Introduction: Hyperprolactinemia is a condition of elevated prolactin levels in blood which could be physiological, pathological, or idiopathic in origin. Some cases of hyperprolactinemia have been reported in patients with renal failure. We present a case of hyperprolactinemia, thyrotropic and corticotropic insufficiency in a patient with end-stage renal failure.Case presentation: The patient was 27 years old, with a history of hypertension, renal insuf...

Introduction: Pituitary adenomas in people over 65 represent less than 10% of all pituitary adenomas, 80% of which are non-functional. Somatotropic adenomas remain very rare. The interest of our study is to describe the clinical, paraclinical and therapeutic profile of cases of senile acromegaly.Patients and methods: This is a retrospective study of four senile acromegaly patients followed in our endocrinology’s department.Res...

Introduction: Glycaemic control is still difficult to achieve despite advances in the pharmacotherapy of type 2 diabetes. Moreover, the COVID-19 crisis led to a disruption in medical consultations and in the access to medications. The aim of our study was to identify factors associated with poor glycaemic control in Tunisian type 2 diabetic patients during the COVID-19 crisis.Methods: This is a cross-sectional study, carried out in December 2021, on type...

Introduction: Chronic hyperglycemia in type 2 diabetic patients is associated with an increased risk of micro and macrovascular complications. Therefore, glycemic control is the cornerstone of its management. The aim of this study was to evaluate glycemic control in patients with type 2 diabetes before and during COVID-19 crisis.Methods: A cross-sectional study was conducted during December 2021, in the outpatient clinic of the department of endocrinolog...

Introduction: Sheehan syndrome represents a rare cause of hypopituitarism. It results from postpartum ischemic necrosis of the pituitary gland. Data evaluating the quality of life in women with Sheehan syndrome are scarce. The aim of this study was to assess the quality of life in patients with Sheehan syndrome and to determine its associated factors.Methods: A cross-sectional study including women with Sheehan syndrome was conducted in the department of...

Introduction: Pallister-Hall syndrome (PHS) is a very rare congenital syndrome, and its exact prevalence is still unknown. The clinical diagnosis is usually made when a hypothalamic hamartoma is associated with polydactyly. Endocrine manifestations consist of hypopituitarism, hypopituitarism, which can affect one or more pituitary axes, and precocious puberty. Here, we report the case of an 18-year-old young man in whom the diagnosis of PHS was delayed until his hospitalizatio...

Introduction: Factitious hypoglycaemia in adults is usually due to exogenous intake of insulin or hypoglycaemia sulfonamides. This occult intake is most often voluntary and the diagnosis is not always obvious.Observation: We report the case of a 37-year-old pregnant woman at 15 weeks of amenorrhoea, followed for addisson’s disease since 3 years and not diabetic, was referred to our department for acute adrenal insufficiency following the discontinua...