Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1398 | Thyroid (non-cancer) | ECE2017

Beware a rapidly enlarging Thyroid mass- a case of Thyroid Lymphoma

Ashraff Suhel , Sharefi Ahmed Al , Nag Satyajit

Primary Thyroid Lymphoma is rare comprising less than 5% among all thyroid malignancies. It is historically associated with Hashimotos thyroiditis. It typically presents as a rapidly enlarging, painless goitre resulting in compression symptoms. Thyroid ultrasound and FNA cytology, using flow cytometry and immunohistochemistry, remain the primary modalities to confirm the presence of lymphoma. Treatment depends on the immunohistology. The prognosis is subtype depended and is ge...

ea0059ep81 | Neuroendocrinology and pituitary | SFEBES2018

Secondary resistance to Cabergoline-pitfalls and challenges of managing macroprolactinoma with high dose dopamine agonist therapy

Abdalaziz Altayeb , Nag Satyajit , Dhakshinamoorthy Barkavi

Dopamine agonists (DA) are first line therapy for Prolactinoma which normalises prolactin(PRL) level in 80% of cases at a median weekly dose of 1 mg. An accepted criterion of pharmacological resistance to DA is failure to normalize PRL levels. We report a case of aggressive macroprolactinoma that required 7 mg of Cabergoline to reduce prolactin despite radiological evidence of tumour shrinkage. A 42 year old male presented with a bitemporal field defect. Imaging confirmed an i...

ea0049ep89 | Adrenal medulla | ECE2017

Should all patients with Neurofibromatosis type 1 undergo biochemical screening for Pheocromocytoma?

Al-Sharefi Ahmed , Ashraff Suhel , Vanka Ramesh , Nag Satyajit

Pheocromocytomas (PHEO) are catecholamine secreting tumours which can occur sporadically or as part of other hereditary/familial syndromes including Neurofibromotosis 1 (NF-1). Unlike the case with other genetic syndromes, the current neurofibromatosis guidelines do not recommend a routine hormonal screening strategy for PHEO in the absence of hypertension or other symptoms. In this paper we describe 2 asymptomatic and normotensive patients with NF-1 where secretory PHEO were ...

ea0034p407 | Thyroid | SFEBES2014

A mediastinal mass in a patient with thyrotoxicosis-recognising the association between thymic hyperplasia and Graves’ disease

Bishop David , Lal Vikram , Fletcher Joanne , Elsaify Wael , Nag Satyajit

Introduction: There is a rare but well documented association between thymic hyperplasia and GravesÂ’ disease particularly in young patients. It is important to recognise this as patients presenting with an anterior mediastinal mass will often undergo extensive investigations to exclude an underlying lymphoproliferative disorder.Case study: A 19-year-old female with symptomatic GravesÂ’ thyrotoxicosis (TSH <0.01 mU/l; FT4 46.8 pmol...

ea0077p158 | Bone and Calcium | SFEBES2021

Immobilization induced hypercalcemia

Khan Irfan Iqbal , Ahmad Waqar , Tahir Chohan Muhammad , Aung Aung , Dhakshinamoorthy Barkavi , Nag Satyajit

Introduction: Immobilization hypercalcemia is uncommon condition associated with limited movements following brain and spinal cord lesions. Immobilization results in stimulation of osteoclastic bone resorption hypercalciuria and hypercalcemia.Case report: 57 year female, Background of Breast Cancer (Treated with Skin sparing mastectomy and adjuvant radiotherapy) admitted following large subdural hematoma leading to craniotomy and evacuation of hematoma. ...

ea0015p43 | Clinical practice/governance and case reports | SFEBES2008

Severe poikilothermia due to hypothalamic injury managed with a portable external heating vest

Mada Srikanth , Shafi Kamaruddin , Jeevan Mettayil , William Kelly , Gavin Young , Simon Ashwell , Nag Satyajit

Introduction: The hypothalamus plays a pivotal role in maintaining body temperature.Insults to the hypothalamus can result in life threatening temperature disturbance.We describe a case of hypothalamic dysfunction presenting with poikilothermia that was managed with a special portable external heating vest.Case report: A 31 year old man presented in July 1992 with a subarachnoid hemorrhage which was managed s...