ea0044oc6.5 | Pregnancy and Reproductive Health | SFEBES2016
Walker Natasha
, Filis Panagiotis
, Soffientini Ugo
, Bellingham Michelle
, O'Shaughnessy Peter
, Fowler Paul
Introduction: The placenta interchanges nutrients, oxygen and waste between mother and fetus, acts as a gate-keeper to protect the fetus and creates an optimal endocrine environment to maintain the pregnancy. Placental insufficiency underpins common pregnancy complications (e.g. intrauterine growth restriction, preterm birth). Perturbed expression of molecular transporter proteins in the placental syncytiotrophoblast will affect fetal exposure to harmful drugs/xenobiotics such...