Endocrine Abstracts

Background: Radioactive iodine (RAI) therapy effectively cures hyperthyroidism although a varying proportion of patients need repeat RAI doses. There is no consensus on the timing of redosing for RAI which varies in different centres between 6 weeks and 12 months depending on the perceived time to respond to therapy.Aim: We have undertaken a retrospective study to assess if after the initial RAI dose of 400 MBq a second RAI dose can be administered earli...

Aim: Bariatric surgery can provide significant weight loss but a complete resolution obstructive sleep apnoea (OSA) cannot be predicted. The aim of our audit was to assess the prevalence of OSA in bariatric clinics and outcomes after malabsorptive bariatric surgery.Methods: Retrospective observational analysis was performed on patients who had undergone bariatric surgery (laparoscopic gastric bypass and sleeve gastrectomy) and completed a minimum of 6 mo...

Case: An 81-year-old man with type 2 diabetes, cerebrovascular disease and hypertension presented with a sudden onset of headache. CT scan and MRI scan of the head did not show any significant abnormality. Headache improved spontaneously and he was discharged with no cause for his headache being identified. Four months later he was diagnosed to have pan-anterior hypopituitarism at another hospital and was commenced on appropriate replacement therapy. Serum prolactin was not el...

Aim: Cinacalcet is a useful treatment option in primary hyperparathyroidism (PHPT) who are managed conservatively; however there are licensing issues and challenges for prescribing in primary care. The aim of our study was to assess the efficacy of cinacalcet treatment in PHPT and benefit of admission avoidance.Methods: Data on patients treated with cinacalcet for PHPT were analysed. PTH, adjusted calcium and vitamin D at initiation, calcium at 6 and 12 ...

Aim: Pre-operative localisation of primary hyperparathyroidism (PHPT) has been based on ultrasound (US) of neck and MIBI scans with an expectation that solitary parathyroid adenomas (PA) would be localised with reasonable accuracy and sensitivity, to enable mini-parathyroidectomy. The aim of our audit was to assess the utility of both these imaging in patients with parathyroid adenoma.Method: Retrospective analysis was performed on all patients who had s...

Aim: Obstructive sleep apnoea (OSA) is widely prevalent in patients with obesity, referred for bariatric surgery. Various clinical tools are clinically used for screening pre-operatively before referring for formal sleep studies. The aim of our observational analysis was to assess the usefulness of various screening methods for OSA used in clinical practice.Methods: Records of all patients who had been referred to bariatric services in 2014 were reviewed...

Background and aim: Fixed dose radioiodine therapy (RAI) is considered to be the standard regime for management of hyperthyroidism although the actual RAI activity used varies between different centres. We have undertaken a retrospective comparison between various outcomes achieved following the use of fixed RAI doses of 400 and 550 MBq at two different centres.Patients and methods: An electronic database has been prepared for all patients who receive RA...

Introduction: Hyperthyroidism secondary to Graves’ disease is well-recognised to be associated with non-thyroidal immunological manifestations like ophthalmopathy and pretibial myxoedema. We report a patient with Graves’ disease who presented with an unusual complication.Case: A 68 year old Caucasian lady presented with typical features of hyperthyroidism which was confirmed by free T4 72.0 pmol/l (12.0–22.0 pmol/l) and TSH <0.01 mU/l ...