Searchable abstracts of presentations at key conferences in endocrinology

ea0013p238 | Neuroendocrinology and behaviour (including pituitary) | SFEBES2007

The effect of exogenous estradiol administration on working memory in the ovariectomised female hooded-lister rat

Sutcliffe Jane , Neill Jo , Marshall Kay

The aim of the investigation was to evaluate the effect exogenous of 17-β-estradiol propionate (E2) on working memory as assessed by the novel object recognition (NOR) paradigm following intermittent or delayed E2 regimens.15 rats were ovariectomised under anaesthesia and were divided into 3 groups namely: (1) vehicle (2) intermittent E2 dosing weeks 1–6 and 13–18, with no treatment weeks 7–12 and (3) delayed (no treatment in weeks 1&...

ea0021p325 | Reproduction | SFEBES2009

Pregnancy adversely affects ability to recall previously seen spatial locations

Farrar Diane , Tuffnell Derek , Neill Jo , Marshall Kay

Background: Female sex steroids influence learning and memory and the neurobiology of brain regions involved in memory processing such as the hippocampus. Pregnancy allows overriding of regulatory feedback loops leading to substantial elevation of endogenous serum hormone levels, depending on concentration; oestradiol can be either neurologically protective or toxic. This investigation aimed to increase understanding of the influence of sex steroids on memory and attention dur...