Searchable abstracts of presentations at key conferences in endocrinology

ea0081p33 | Calcium and Bone | ECE2022

Psychometric evaluation of the hypoparathyroidism symptom diary using data from two clinical trials

Nelson Lauren , Ing Steven , Rubin Mishaela , Ma Jia , Martin Susan , Sen Rohini , Ayodele Olulade

The Hypoparathyroidism Symptom Diary (HypoPT-SD) was developed for the daily assessment of key symptoms and impact of HypoPT as reported by patients with chronic HypoPT and includes 13-items: a 7-item Symptom subscale, 4-item Impact subscale, and single-item anxiety and depression scores. The current analysis was undertaken to confirm test-retest reliability and construct validity of HypoPT SD Symptom subscale scores using data collected during two open-label, single-arm studi...

ea0049ep1263 | Thyroid (non-cancer) | ECE2017

Psychometric evaluation of the newly developed hypoparathyroidism symptom diary

Coles Theresa , Chen Kristina , Nelson Lauren , Harris Nimanee I , Vera-Llonch Montserrat , Martin Susan

Objective: The purpose of this study was to evaluate the psychometric properties of a novel, patient-reported outcome (PRO) measure, the Hypoparathyroidism (HPT) Symptom Diary (HPT-SD), using data collected during a cross-sectional, noninterventional, observational study. The HPT-SD, developed according to the US Food and Drug Administration PRO guidance, addresses the severity of key symptoms (muscle cramping, tingling and muscle spasms/twitching, fatigue, cognition, emotions...