Searchable abstracts of presentations at key conferences in endocrinology

ea0037s7.2 | Novel mechanisms of central weight regulation | ECE2015

Regulation of hypothalamic development by maternal nutrition

Vogt Merly , Paeger Lars , Hess Simon , Steculorum Sophie , Neupert Susanne , Predel Reinhard , Kloppenburg Peter , Horvath Tamas , Bruning Jens

In light of the ever-increasing incidences of obesity and T2DM, development of novel therapeutic or preventative measures to combat these epidemics is of utmost importance. Identification of a causal relationship between an altered maternal metabolic homeostasis and an increased propensity for the unborn child to develop metabolic disorders throughout lifetime has shifted considerable amount of attention towards understanding the underlying cellular and molecular alterations. ...