Searchable abstracts of presentations at key conferences in endocrinology

ea0031oc2.2 | Steroids and thyroid | SFEBES2013

Abnormal cardiac bio-energetics in subclinical hypothyroidism; cardiac magnetic resonance spectroscopic study

Madathil Asgar , Hollingsworth Kieren , Razvi Salman , Blamire Andrew , Taylor Roy , Newton Julia , Weaver Jolanta

Background: It is well established that subclinical hypothyroidism (SCH) is associated with mild ventricular dysfunction and early cardiovascular disease (CVD), but it is unknown if there is an underlying defect in cardiac bio-energetic function.Objective: To quantify the cardiac phosphocreatine/ATP (PCr/ATP) ratio in SCH, compare with healthy controls (HC) and to measure the effect of 6 months of thyroxine treatment.Method: Cardia...