Endocrine Abstracts

Purpose: To evaluate long-term safety and efficacy of cinacalcet in management of primary hyperparathyroidism (PHPT).Material/Methods: We retrospectively studied all patients on cinacalcet for primary hyperparathyroidism over 3 year’s period. Data was collected and analyzed for indication, daily maintenance dose, tolerability, biochemical effect at 3, 6 and 12 months, effect on bone mineral density and renal stone disease. This study excluded those ...

Background: The treatment goal in primary hyperparathyroidism (PHPT) is the achievement of biochemical control and prevention of target organ complications. Parathyroidectomy is the current recommended intervention to cure the disease. However, Cinacalcet is an alternative medical treatment for subgroup of patients in whom surgery is deemed inappropriate, those with recurrent disease, and as bridging therapy for delayed operation particularly in recent COVID pandemic. Current ...

Background: Calcitriol-induced hypercalcemia is uncommon posing diagnostic dilemma. This case report describes a patient with severe hypercalcemia due to granulomatous changes around a polyethylene wear hip prosthesis.Case Report: An 80-year-old woman presented with hypercalcemia and stage 3 acute kidney injury. Serum calcium was 3.9 mmol/l, Parathyroid hormone 0.2 pmol/l(1.3 - 9.3), confirming PTH-independent hypercalcemia. CT and MRI imaging, tumor mar...