Endocrine Abstracts

18 year old student was referred by the Gynaecology team with primary amenorrhoea, delayed puberty, and minimum breast development. History: The patient was born by an emergency caesarean section with a birth weight of eight pounds and four ounces. She had a normal development during infancy and childhood and there was no reported developmental delay in the family. She had adrenarche at the age of ten with a normal appearance of axillary and pubic hair....

17 year old male was referred by GP with short stature and delayed development of secondary sex characteristics. History: He was born at full term with a bodyweight of eight pounds and normal development till adolescence. He is the second out of three children and as his parents and siblings entered puberty at expected ages and he has not suffered from the chronic illness make constitutional delay of puberty or functional hypothalamic hypogonadism less l...

Hypophysitis is an inflammatory disorder of the pituitary gland and among them, IgG-4 hypophysitis is rare and presents in less than 5 % of cases.Case: 59 years old lady with a past medical history of asthma presented Rheumatology with? giant cell arthritis due to constant frontal headache, pain behind her eyes, and raised inflammatory markers (ESR 15, CRP 17) three weeks after COVID infection. After review, rheumatology team concluded unlikely giant cel...

Introduction: Crooke’s cell adenomas are nonneoplastic corticotropes with cytoplasmic accumulation of cytokeratin filaments in response to glucocorticoid excess. They are rare subtype of corticotrope adenomas presenting less than 1 % of pituitary adenomas.Case: 52 years old man attended Ophthalmology Clinic with 2 months history of right-sided reduced vision. He had a history of posterior polymorphous corneal dystrophy with a left corneal transplant...