Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1323 | Paediatric endocrinology | ICEECE2012

Kearns-Sayre syndrome: clinical and molecular diagnosis of the disease and treatment with recombinant GH (rGH) complicated by a severe cardiac conduction deficit and cardiomyopathy

Obara-Moszynska M. , Maceluch J. , Bobkowski W. , Baszko A. , Jaremba O. , Krawczynski M. , Niedziela M.

Introduction: Kearns-Sayre syndrome (KSS) is a rare mitochondrial cytopathy. The diagnosis of KSS is made on the classical triad of symptoms: onset of the disease <20 years of age, progressive external ophthalmoplegia (PEO) and pigmentary retinopathy (PR). KSS is manifested also by other systemic abnormalities: cardiac conduction defects, different neurological abnormalities and several endocrine disorders. A variety of deletions and/or duplications in mtDNA, affecting gen...

ea0029p435 | Clinical case reports - Thyroid/Others | ICEECE2012

Reversible Hashimoto’s thyroiditis: clinical, hormonal, autoimmune and ultrasonographic evidence

Niedziela M.

Introduction: HashimotoÂ’s thyroiditis (HT) and Graves' disease (GD) constitute a spectrum of autoimmune thyroid diseases (AITD). An abnormal thyroid echographic pattern characterized by a diffuse low echogenicity has been described in both AITD. This hypoechogenicity is due to three components: increase of intrathyroidal flow, functional changes in thyroid follicles with increased cellularity and decrease of the colloid content, resulting in the reduction of the cell/coll...