Searchable abstracts of presentations at key conferences in endocrinology

ea0090p554 | Adrenal and Cardiovascular Endocrinology | ECE2023

Unexpected cause of hypertension associated with hypokalemia

Trifanescu Raluca , Toma Iustin-Daniel , Mohora Maria-Alexandra , Popescu Ileana , Nitu Ileana , Poiana Catalina

Background: Prolonged ingestion of licorice has been known to cause hypokalemia and resistant hypertension amongst other disturbances. This is due to glycyrrhizin that inhibits the 11-β-hydroxysteroid dehydrogenase enzyme type 2 which results into increased plasma cortisol levels that stimulate the mineralocorticoid receptors resulting into apparent mineralocorticoid excess.Case report: A 45-year-old woman resident in an iodine sufficient area, heav...

ea0041ep748 | Neuroendocrinology | ECE2016

Severe carcinoid cardiac disease in a young patient with neuroendocrine tumor of unknown origin

Poiana Catalina , Nitu Ileana , Baciu Ionela

Carcinoid cardiac disease is a rare cause of intrinsic right heart valve disease with significant impact on mortality. We present the case of a young male patient (38 yrs old) complaining in the last 5 yrs of abdominal pain associated with flushing of the face that progressively worsened (up to 15 episodes/day) accompanied by diarrhoea and, in the last 2 months, by night sweats, distension of the abdomen, bilateral ankle swelling and progressive limitation in effort. Endocrine...

ea0099p244 | Adrenal and Cardiovascular Endocrinology | ECE2024

Cardiovascular risk in patients with primary hyperparathyroidism

Trifanescu Raluca , Mohora Maria , Toma Iustin , Nitu Ileana , Poiana Catalina

Background: PTH is a hormone with vascular and cardiovascular properties, involved in the expression of endothelial pro-atherosclerotic and pro-inflammatory parameters. Both hypercalcemic and normocalcemic primary hyperparathyroidism (PHPT) were associated with increased cardiovascular risk.Patients and methods: 84 patients (6M/78F) with PHPT, aged 58.9±12.7 years, were retrospectively reviewed. Serum calcium levels, PTH and 25 OH vitamin D levels w...

ea0073aep539 | Pituitary and Neuroendocrinology | ECE2021

Assessing quality of life and cardio-vascular risk in patients with acromegaly: A single tertiary center case series

Morea Alexandru , Lambrinoc Diana , Nitu Ileana , Baciu Ionela Florina , Poiana Catalina

BackgroundAcromegaly is a rare disease, caused by an autonomous excessive secretion of growth hormone (GH). Apart from skeletal alterations, the GH excess leads to metabolic and visceral disease. Thus, one of the most frequent associated complications is the cardio-vascular one represented by hypertension, cardiomyopathy and ischemic heart disease. The presence of multiple complications in patients with acromegaly leads not only to increased morbidity an...

ea0073aep672 | Thyroid | ECE2021

Side-effects of calcitonin stimulation tests with calcium gluconate

Baetu Mara , Olariu Cristina , Nitu Ileana , Moldoveanu Gabriel , Corneci Cristina , Badiu Corin

IntroductionOver time, different substances and protocols have been used and tested for stimulating calcitonin (CT). Some of them proved to be useful in diagnosing medullary thyroid carcinoma (MTC). However, these are associated with side-effects, with various duration, intensity and severity.ObjectiveTo report the side-effects observed during CT stimulation test with calcium (Ca) gluconate.<p class="abst...

ea0081p743 | Thyroid | ECE2022

Concomitant Graves′ disease with COVID-19 infection

Trifanescu Raluca , Toma Iustin-Daniel , - Alexandra Mohora Maria , Cristina Corneci Marioara , Nitu Ileana , Baloseanu Nicoleta , Vladoiu Suzana , Schipor Sorina , Dumitrascu Anda , Poiana Catalina

Background: Subacute thyroiditis, autoimmune thyroiditis and an atypical form of thyroiditis due to primary injury of the thyroid gland by SARS Cov2 itself are complications of COVID-19. Angiotensin-converting enzyme 2 is also expressed in the thyroid gland. On the other hand, both untreated thyrotoxicosis and COVID-19 affects heart, generating cardiac complications.Case report: A 36-year-old woman resident in an iodine sufficient area, heavy smoker, pre...

ea0090ep851 | Pituitary and Neuroendocrinology | ECE2023

Echocardiographic features in patients with prolactinoma long-term treated with dopamine agonists

Carmen Giuca Diandra , Constantin Vere Cristin , Nitu Ileana , Capatina Cristina , Baciu Ionela , Florentina Burcea Iulia , Baculescu Nicoleta , Radian Serban , Simona Andreea Găloiu , Trifanescu Raluca , Poiana Catalina

Background: Dopamine agonists (DAs) were associated with valvular dysfunction in patients with Parkinson’s disease due to their fibrotic effect through the serotoninergic receptor. It is more difficult to prove the same effects in patients with prolactinoma due to the lower doses, variable doses and the longer follow-up period. Aim: To assess echocardiographic features in patients with prolactinoma under DA treatment.Methods: ...

ea0090ep741 | Pituitary and Neuroendocrinology | ECE2023

Vitamin D status and cardiovascular risk in a cohort of acromegalic patients

Toma Iustin-Daniel , Trifanescu Raluca , Mohora Maria-Alexandra , Baciu Ionela , Baculescu Nicoleta , Burcea Iulia Florentina , Capatina Cristina , Dusceac Roxana , Andreea Găloiu Simona , Niculescu Dan Alexandru , Nitu Ileana , Radian Serban , Poiana Catalina

Background: Vitamin D deficiency is the most common nutritional deficiency, estimated to affect almost one billion people worldwide. Multiple factors influence 25(OH)D levels: nutrition, sunlight exposure, outdoor physical activity, skin color. Patients with active acromegaly (AA) have lower 25(OH)D levels compared with healthy population and are at a higher risk to develop vitamin D deficiency. Also, some studies have suggested a possible protective role of vitamin D on the c...