Searchable abstracts of presentations at key conferences in endocrinology

ea0010dp8 | Diabetes, metabolism and cardiovascular | SFE2005

Circulating alanine aminotransferase (ALT) is elevated in obese women with PCOS, and is reduced by protracted metformin treatment

Fleming R , Harborne L , Norman a J , Sattar N

Serum ALT concentrations give some insight into liver fat accumulation and relate to metabolic syndrome: values>29 IU/L double risk of type 2 diabetes independent of other risk predictors. Women with PCOS are at increased risk of diabetes and CVD whereas metformin treatment modulates the progress of metabolic syndrome. Consequently, we investigated the effects of protracted metformin treatment on circulating ALT in obese women with PCOS.Methods<p...