Searchable abstracts of presentations at key conferences in endocrinology

ea0014p588 | (1) | ECE2007

Hypopituitary patients have an increased prevalence of cardiovascular risk factors

Matuszek Beata , Kowalczyk Mariusz , Zapolski Tomasz , Nowakowski Andrzej

Introduction: Hypopituitary patients receiving conventional hormone replacement, but without GH replacement, have an increased mortality from cardiovascular diseases. Inadequate hormone replacement is a possible cause of this increased mortality. GH deficiency in adult patients has been associated with several cardiovascular risk factors, including hyperlipidemia, increased abdominal adiposity, and impaired insulin sensitivity.The aim of the study is an ...

ea0032p405 | Diabetes | ECE2013

Correlations between umbilical and maternal adiponectin as well as neonatal birthweight

Matyjaszek-Matuszek Beata , Burska Agata , Gernand Wojciech , Lenart-Lipinska Monika , Nowakowski Andrzej , Paszkowski Tomasz

Introduction: Adiponectin (AdipoQ) is a known insulinsensitizing adipokine which is also present in fetal circulation. It has been postulated to play a role in the regulation of fetal growth and development together with other adipokines. The aim of the study was to determine fetal adiponectin and find its correlations with the neonatal birthweight and maternal AdipoQ.Patients and methods: The study included 36 women with singleton pregnancy (20 diagnose...

ea0032p408 | Diabetes | ECE2013

Fibroblast growth factor 21: a new predictor of cardiovascular events in type 2 diabetes

Lenart-Lipinska Monika , Matyjaszek-Matuszek Beata , Gernand Wojciech , Solski Janusz , Nowakowski Andrzej

Introduction: The course of type 2 diabetes (DM2) is linked with increased fibroblast growth factor 21 (FGF21) concentrations, however little information is available on the prognostic significance of FGF21 in DM2. The aim of the study was to assess whether FGF21 may be a predictor of cardiovascular (CV) events in patients with DM2.Patients and methods: The study comprised 87 patients with DM2, aged 57–66 years, with the median duration of diabetes ...

ea0022p368 | Diabetes | ECE2010

Comparative evaluation of serum concentrations of a novel adipocytokine, fibroblast growth factor-21 in patients with type 2 diabetes and obesity

Matuszek Beata , Lenart-Lipinska Monika , Duma Dariusz , Solski Janusz , Nowakowski Andrzej

Fibroblast growth factor-21 (FGF-21) is a novel adipocytokine, which is believed to be involved in improvement of insulin sensitivity and pathogenesis of type 2 diabetes.The aim of the study was comparative assessment of FGF-21 concentrations in serum of patients with type 2 diabetes and evaluation of possible relationships between the studied cytokine and selected clinical and biochemical parameters.Forty-four patients with type 2...

ea0014p50 | (1) | ECE2007

Prevalence of GADA and IAA in elderly patients with type 2 diabetes

Kurowska Maria , Tarach Jerzy S , Jankowska Helena , Kowalczyk Mariusz , Malicka Joanna , Nowakowski Andrzej

Little is known about the prevalence and significance of islet cell immunity in elderly patients with type 2 diabetes. The low antibody titers against islet-cell antigens in LADA elderly patients may be a sign of a less aggressive autoimmune diabetes.The objective: To establish the changing frequency and titers of GADA and IAA in elderly diabetics.Material: 83(56F;27M)diabetic patients (60–91 y) divided in age related groups. ...

ea0032p349 | Diabetes | ECE2013

Expression of adiponectin gene and adiponectin receptors in placental and adipose tissue in women with gestational diabetes mellitus

Matyjaszek-Matuszek Beata , Kowalczyk Mariusz , Lagowska-Batyra Agnieszka , Gernand Wojciech , Nowakowski Andrzej , Leszczynska-Gorzelak Bozena , Kocki Janusz

Introduction: Adiponectin shows its beneficial insulin-sensitizing properties, however, women with gestational diabetes mellitus (GDM) present hypoadiponectinemia.Aim of the study: To assess the expression of adiponectin gene as well as its AdipoR1 and AdipoR2 receptors in placenta and adipose tissue and to determine potential correlations with chosen metabolic parameters (clinical and biochemical).Patients and methods: Thirty-six ...

ea0014p51 | (1) | ECE2007

Comparison of plasma homocysteine concentrations (HYC) in patients with acute coronary syndrome (ACS) and newly or previously diagnosed type 2 diabetes

Kurowska Maria , Tarach Jerzy S , Gernand Wojciech , Kudlicki Janusz , Tarkowski Adam , Nowakowski Andrzej , Czekajska Teresa , Solski Janusz

Introduction: The patients with ACS and scheduled for an elective coronary angiography have high frequency of both newly and previously diagnosed diabetes. The diabetic patients with acute myocardial infarction have an increased risk of death. Elevated blood HYC is strongly related to an increased risk for atherosclerosis and cardiovascular disease. This association is particularly evident in patients with diabetes.Aim of the study: An attempt to evaluat...