Endocrine Abstracts

Peripheral artery disease (PAD); is a chronic occlusive disease in lower extremities. PAD is an important sign of atherosclerosis, and an important predictor of mortality and morbidity during the cerebrovascular and cardiovascular diseases. Since the cardiovascular diseases are the most important cause of death in type 2 DM patients, diagnosing the mortality and morbidity predictor PAD in the early period is very important. The ankle–brachial index is an easy and cheap me...

A lactating 31-year-old woman who developed L5 vertebral compression fracture 2 months after the delivery of her first child is presented. Serum concentrations of Ca was 10.24 mg/dl (8.6–10.2 mg/dl), phosphorus was 4.1 mg/dl (2.7–4.5 mg/dl), albumin was 4.6 mg/dl, ALP was 210 U/l (35–105 U/l), PTH was 13.8 pg/ml (15–65). There was axial osteoporosis, as assessed by dual-energy X-ray absorptiometry. Z score; L1 (−3), L2 (−3.8), L3 (&#872...

Bilateral macronodular or micronodular adrenal hyperplasias are related to ACTH-independent or ACTH-dependant pathologies. ACTH-independent bilateral macronodular adrenal hyperplasia (AIMAH) and primary pigmented adrenocortical disease (PPNAD) are classical but rare examples of ACTH-independent pathologies, causing Cushing Syndrome. PPNAD is presented as bilateral micronodular adrenal hyperplasia.On the other hand, inherited defects in the enzymatic step...

A 27 year-old-man was admitted to our hospital with pain in the back. Bone mineral density evaluation revealed severe osteoporosis at L1–L4 vertebrae, as well as on femur, too. Secondary osteoporosis reasons like thyrotoxicosis, glucocorticoid therapy, hypercortisolemia, hypercalciuria, hyperparathyroidism were excluded. Laboratory examination of the patient revealed to a hypoglobulinemia. Further evaluation of the immunoglobulin levels were in concordance with panhypoglo...

We report the MRI findings of an unusual case of posterior pituitary ectopia (PPE) in a young female patient with idiopathic diabetes inspidus (DI). She was 29 years- old and presented with polydipsia (7–8 lt/day), and polyuria (7–8 lt/day) that had been present for about 5 months. She had regular menstrual cycles. She didn’t have any history of significant medical illness or any history of head trauma. An 8-hour fluid deprivation test followed by desmopressin (...

The patient had been diagnosed with congenital adrenal hyperplasia (CAH) at age 5 because of precocious of puberty. He had been receiving dexamethazone and fludrocortisone therapy over the course of his life. When he was 16 years old, a scrotal ultrasound had been performed for the evaluation of bilateral testicular pain which revealed multiple sharply marginated, hypoechoic masses throughout both testes. A biopsy of left testis had been reported as ‘Leidig cell tumour&#1...

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

Seckel syndrome (SS) is a rare disorder of severe growth retardation and craniofacial-skeletal abnormalities. In scant number of reports, neonates had intact hypothalamic–pituitary–adrenal axis before they die because of cardiopulmonary abnormalities. We present an unique case of SS at the age of 18 years and discuss the possible explanations of his growth retardation and sex reversal.Case: A 18-year-old female presented with short stature and ...