Searchable abstracts of presentations at key conferences in endocrinology

ea0016p637 | Reproduction | ECE2008

Topographical effects of functional prostanoid and oxytocin receptors on mid-cycle contractions in isolated human myometrium

Fischer Deborah , O Donovan Peter , Farrar Diane , Woodward David , Marshall Kay

Dysfunctional prostanoid and oxytocin receptors have been implicated in the development of myometrial hyperactivity, causing dysmenorrhoea and infertility. The aim of the present study was to investigate the topographical differences in functional contractile PG and oxytocin receptors in mid-cycle isolated myometrium.Longitudinal, full-thickness sections of the anterior uterus were obtained from consenting pre-menopausal donors (aged 39–48 years) un...

ea0016p643 | Reproduction | ECE2008

Simultaneous profile of prostanoids in pregnant preterm non labouring, term non labouring and term labouring myometrium using ESI-LC-MS

Durn Joanne , Marshall Kay , Nicolaou Anna , Farrar Diane , O' Donovan Peter , Woodward David

The aim of this study was to simultaneously profile, using electrospray ionization liquid chromatography mass spectrometry (ESI-LC-MS), prostanoids (PG) produced in samples of: pregnant preterm non labouring (PTNL); term non labouring (TNL): and term labouring (TL) myometrium.Lower segment samples were obtained at Caesarean section from consenting pregnant women (18–36 years of age) at term (38–41 weeks) and preterm (33 weeks) gestation. Sample...