ea0003p125 | Endocrine Tumours and Neoplasia | BES2002
Guy M
, Lowe L
, Oades G
, Bretherton-Watt D
, Mansi J
, Colston K
Prostate and breast cancers remain common causes of cancer related deaths in the UK. The majority of cases appear to be of a multifactorial aetiology that includes a genetic component. It has been suggested that low levels of circulating 1,25 dihydroxyvitamin D3 are associated with an increased risk of both breast and prostate cancer. A number of polymorphisms in the vitamin D receptor (VDR) gene have been identified resulting in differing genotypes that may alter s...