Searchable abstracts of presentations at key conferences in endocrinology

ea0014p519 | (1) | ECE2007

Investigation of early atherosclerotic changes in acromegalic patients

Kartal Ilkay , Oflaz Huseyin , Pamukcu Burak , Aral Ferihan , Ozbey Nese , Alagol Faruk

Background: Functional and morphological changes of endothelium are risk factors for mortality attributed to atherosclerosis. Studies investigating early atherosclerotic alterations and the effect of the treatment of acromegaly on these alterations gave conflicting results.Objective: Surrogate markers of early atheosclerotic changes, i.e. brachial artery flow-mediated dilation (FMD) and carotid artery intima-media-thickness (IMT) in active and inactive a...

ea0016s30.4 | Clinical highlights | ECE2008

Evaluation of endothelial function and endothelial nitric oxide synthase intron 4a/b polymorphism in primary hyperparathyroidism

Ekmekci Ahmet , Abaci Neslihan , Agayev Ayaz , Aksakal Nihat , Oflaz Huseyin , Unaltuna Nihan Erginel , Erbil Yesim , Ozbey Nese Colak

The aim of this study is to evaluate endothelial function in patients with primary hyperparathyroidism (pHT) during the preoperative hypercalcemic and postoperative normocalcemic periods and to determine whether intron 4a/b polymorphism of eNOS gene influences endothelial function. Forty-one patients with pHT (28 women, 12 men; age: 48.4±11.6 years, serum calcium: 11.4±1.0 mg/dl, parathyroid hormone: 373.3±394.5 pg/ml) who fulfilled the criteria for parathyroid ...