Searchable abstracts of presentations at key conferences in endocrinology

ea0104p88 | Diabetes & Metabolism | SFEIES24

Insulin-releasing and glucose-lowering effects of gallic acid in cellular and high fat-fed mice models of type 2 diabetes

Ojo Opeolu , Falana Ayokunle , Falobi Ayodele , Heer Simren , Adie Mojisola , Edeani Joy , Ojo Constance

Aim: Gallic acid is one of the major bioactive phenolic compounds that have been isolated from several plant extracts with reported antidiabetic actions. However, insulinotropic effects and mechanisms underlying antidiabetic actions of garlic acid is poorly understood. This study investigated insulin-releasing and glucose-lowering effects of gallic acid.Methods: Glucose-stimulated insulin secretion in BRIN-BD11 cells were examined in the absence or prese...