Searchable abstracts of presentations at key conferences in endocrinology

ea0035p370 | Diabetes (epidemiology, pathophysiology) | ECE2014

Compensatory increased irisin levels in gestational diabetes mellitus

Arkan Tugba , Calan Mehmet , Cimrin Dilek , Yesil Pinar , Oktan Mehmet Asi , Aygun Kemal , Bayraktar Firat

Context: Irisin, a newly discovered hormone, is secreted by skeletal muscles into circulation. It is proposed to regulate energy homeostasis and hold therapeutic potential in diabetes and obesity.Objective: We aimed to investigate the association of irisin and uncoupling protein 1 (UCP1) with gestational diabetes mellitus (GDM).Design and Setting: This was a cross-sectional study conducted in a university hospital.<p class="abs...

ea0035p383 | Diabetes (epidemiology, pathophysiology) | ECE2014

Low apelin levels are associated with a marked increase in risk for development of the gestational diabetes mellitus

Oktan Mehmet Asi , Calan Mehmet , Calan Ozlem , Cimril Dilek , Eraslan Sevinc

Introduction: Apelin is an adipokine which plays a role in the regulation of glucose homeostasis. The relationship between apelin serum concentration and dysmetabolic conditions such as type 2 diabetes (T2D) is still controversial. The aim of our study was to investigate the association of apelin with gestational diabetes mellitus (GDM).Design and methods: This study was designed as a cross-sectional research that consecutively recruited subjects with GD...

ea0037ep153 | Reproduction, endocrine disruptors and signalling | ECE2015

A possible link between LH and macrophage migration inhibitory factor levels in polycystic ovary syndrome

Calan Mehmet , Kume Tuncay , Yilmaz OzgUr , Arkan Tugba , Kocabas Gokcen Unal , Dokuzlar Ozge , Aygun Kemal , Oktan Mehmet Asi , Danis Nilay , Temur Muzaffer

Purpose: Macrophage migration inhibitory factor (MIF) is a multi-functional cytokine which plays a role in metabolic and inflammatory processes. Increasing evidence suggests that there is a link between MIF and ovulation. We aimed to evaluate plasma MIF levels in women with polycystic ovary syndrome (PCOS) and to determine whether MIF levels differ between the follicular phase and mid-cycle of the menstrual cycle in eumenorrheic women.Methods: Ninety wom...