Searchable abstracts of presentations at key conferences in endocrinology

ea0090p433 | Pituitary and Neuroendocrinology | ECE2023

Lanreotide-Induced Acalculous Acute Pancreatitis in a Person with Acromegaly: an Unexpected Severe Side Effect

Ramalho Diogo , Alves Helena , Henrique Carmona Alexandrino Jorge , Jesus Nuno , Melo Gustavo , Joao Oliveira Maria

Introduction: Somatostatin analogues (SA) are the first-line treatment for Acromegaly in patients whose surgery failed to achieve cure or it was contraindicated. The main reported adverse events of SA are mild and transient, and include nausea, abdominal cramps, diarrhea and flatulence. Other side effects are of rare occurrence.Case report: The authors describe a case of a 44-year-old previously asymptomatic male patient with a growth hormone-secreting p...

ea0049ep145 | Clinical case reports - Thyroid/Others | ECE2017

Insulinoma masquerading as neurologic disease

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Oliveira Maria Joao

Introduction: Insulinomas are the most frequent cause of hypoglycemia and the most common functional endocrine pancreatic tumors. Whipple triad is often present and should alert to the diagnosis.Case report: A 36-year-old male was admitted in the emergency room with loss of consciousness, diaphoresis and blurred vision, and hypoglycemia (50 mg/dl). The patient recalled recurrent symptoms of diaphoresis, tremors and palpitations, sometimes with loss of co...

ea0049ep818 | Paediatric endocrinology | ECE2017

Turner Syndrome (TS): overview of surveillance in a tertiary care hospital

Popik Ekaterina , Matos de Figueiredo Catarina , Freitas Joana , Cardoso Helena , Joao Oliveira Maria , Borges Teresa

Introduction: Turner syndrome is one of the most common human chromosomopathy and represents an important cause of short stature and ovarian insufficiency. It is caused by total or partial loss of X-chromosome and its prevalence is about 1 in 2000–2500 live female births.Objectives: To review the patients with TS followed in a Paediatric Endocrinology Unit since 1999.Methods: A retrospective study regarding diagnosis, course, ...

ea0049ep923 | Paediatric endocrinology | ECE2017

Growth hormone deficiency – the experience of one pediatric endocrinology unit of a Portuguese hospital in the last 5 years

Ferreira Jorge Abreu , Barroso Fabio , Martins Cristiana , Freitas Joana , Cardoso Helena , Oliveira Maria Joao , Borges Teresa

Introduction: Hypopituitarism is a clinical syndrome of deficiency in growth hormone (GHD) production, which can occur isolated or associated with others pituitary defects. GHD has an incidence of 1:4000 to 1:10 000. It may be idiopathic, congenital or acquired.Purpose: Characterize the paediatric population with GHD followed at the Paediatric Endocrinology Unit of our centre and compare the clinical presentation and treatment response of the patients wi...

ea0049ep1211 | Clinical case reports - Thyroid/Others | ECE2017

Thyroid storm subsequent to amiodarone-induced thyrotoxicosis

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Oliveira Maria Joao

Introduction: Thyroid storm is a rare medical emergency with high mortality, which usually results from acute exacerbation of hyperthyroidism. Amiodarone is a highly used class III antiarrhythmic drug and amiodarone-induced thyrotoxicosis is an infrequent effect of this medication, whose treatment may be difficult.Case study: A 20-year old male with congenital cardiomyopathy (Fallot tetralogy and Ebstein anomaly), chronically medicated with amiodarone 20...

ea0049ep1351 | Thyroid (non-cancer) | ECE2017

Outcome of radioiodine therapy in patients with hyperthyroidism

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Silva Fernando , Oliveira Jose Manuel , Oliveira Maria Joao

Introduction: Radioiodine treatment (RAIT) is an effective definitive treatment for Graves’ Disease (GD) and Toxic Nodular Goiter (TNG). The aim of this study was to analyze demographic and clinical factors affecting the outcome of RAIT in patients with hyperthyroidism.Methods: Retrospective review of patients treated with RAIT for hyperthyroidism. A fixed dose of 10 mCi was administered to patients with GD and 15 mCi to patients with TNG. Treatment...

ea0041ep11 | Adrenal cortex (to include Cushing's) | ECE2016

ARMC5 mutation and Cushing syndrome due to bilateral macronodular adrenal hyperplasia – case report

Manuel Costa Maria , Oliveira Joana , Luis Castedo Jose , Magalhaes Joao , Carvalho Davide

Introduction: Bilateral macronodular adrenal hyperplasia ACTH-independent (BMAH) represents less than 1% of the causes of Cushing’s syndrome (CS). Studies have shown that mutations in the gene ARMC5 are a common cause of family BMAH and are associated with severe clinical disease and the development of meningiomas.Case report: 64-years-old man presented to our consult due to bilateral macronodular adrenal hyperplasia. He had diabetes mellitus, arter...

ea0070ep308 | Pituitary and Neuroendocrinology | ECE2020

Insipidus diabetes and vaginal ulcers... evidence for the diagnosis of langerhans cell hypophysitis

Correia Sara , Melo Gustavo , Alves Helena , Almeida Lucia , João Oliveira Maria , Ramalho Diogo

Introduction: Langerhans Cell Histiocytosis (HCL) is a rare granulomatous disease, unknown etiology, with a wide clinical spectrum. The pituitary is affected in 25% of cases, with diabetes insipidus being the earliest and most frequent feature. Although it is more common in pediatric age, it can also be developed by adults.Clinical case: A 39-year-old, caucasian, woman presents with polydipsia with 5L/day of water and an appetite for cold drinks, polyuri...

ea0073pep14.1 | Presented ePosters 14: COVID-19 | ECE2021

Is initial hypocalcemia related to poorer outcomes in COVID-19 patients?

Alves Helena , Ferreira Marta Almeida , Almeida Lucia , Correia Sara , Ramalho Diogo , João Oliveira Maria

IntroductionAlthough most patients with COVID-19 have mild symptoms, some develop severe manifestations of the disease, leading to hospitalization and death. Previous studies reported that calcium played a central role in viral infections and replicative mechanisms of SARS-CoV. Hypocalcemia is a common finding among these patients. The aim of this study was to investigate the prevalence of hypocalcemia in a population of COVID-19 patients and to evaluate...

ea0092ps3-22-09 | Nodules 2 | ETA2023

Percutaneous ethanol sclerotherapy for the treatment of benign cystic thyroid nodules: A 5 year-experience at a tertiary care hospital

Carmona Alexandrino Henrique , Ramalho Diogo , Machado Catarina , Jesus Nuno , Ferreira Marta , Rocha Gustavo , Joao Oliveira Maria

Objectives: Assess the efficacy and safety of ultrasound-guided percutaneous ethanol injection (PEI) for treating benign cystic or predominantly cystic-thyroid nodules (TN).Methods: Retrospective analysis of all euthyroid patients treated with PEI for purely (>90% of cystic component) or predominantly cystic (50%-90% of cystic component) TN between January 2018 to February 2023. Efficacy was defined as 50% or greater reduction in pretreatment volume ...