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ea0037ep678 | Pituitary: basic and neuroendocrinology | ECE2015

Long-term safety, tolerability, and efficacy of extended release somatostatin analogues

Gonzalez Javier , Garcia-Centeno Rogelio , Arnoriaga Maria , Picallo Maria , Ramirez Maria Laura , Andia Victor Manuel , Olmedilla Yoko Lucia , Lopez Aurelio , Monereo Susana

Introduction: The main indications for the somatostatin analogues (SST-A) are acromegalies and/or neuroendocrine tumors. They can increase fecal fats, which could lead to the loss of fat soluble vitamins. There are few published studies showing the effects of the long-term use.Methods: Retrospective study of patients with SST-A indicated from our endocrinology department in the last 10 years. We analysed indications and different epidemiological, clinica...

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ea0049ep1030 | Pituitary - Clinical | ECE2017

Hormone and tumor responses to primary or pre-operative therapy with somatostatin analogs in acromegaly and the relation with T2-weighted MRI signal

Picallo Maria , Centeno Rogelio Garcia , Guerra Aurelio Lopez , Olmedilla Yoko Lucia , Arnoriaga Maria , Requena Maria , Agreda Javier , Andia Victor , Sambo Marcel , Monereo Susana , Velez Maria Angeles , Weber Bettina , Atencia Jose

Objective: Study of the efficacy of SSA in the biochemical and tumour control and the relation between the T2-weighted MRI signal intensity and the response to SSA.Material and methods: 16 patients with GH-secreting pituitary adenomas (7♂/9♀) that received primary or pre-operative treatment with SSA. We classified them according to baseline T2-weighted MRI sequences as Hypo-intense (Ha) and No-Hypo-intense adenomas (no-Ha). Results expressed ...

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Endocrine Abstracts

Long-term safety, tolerability, and efficacy of extended release somatostatin analogues

Hormone and tumor responses to primary or pre-operative therapy with somatostatin analogs in acromegaly and the relation with T2-weighted MRI signal

BiosciAbstracts