Endocrine Abstracts

Parvovirus (Erythrovirus) B19 (EVB19) infection may trigger autoimmune diseases like SLE, RA, and vasculitis. Parvovirus B19 belongs to the parvoviridae family and to the erythrovirus genus. The etiopathogenesis of autoimmune diabetes mellitus could not been explained yet. The aim of our study was to investigate whether EVB19 may have a role in the etiopathogenesis of type 1 DM. Therefore have we examined whether EVB19 is more frequent among type 1 diabetics. 32 patients with ...

: Erythrovirus (EVB19) can recognize auto-antigens by using molecular mimicry mechanisms. EVB 19 is accused in the pathogenesis of many autoimmune diseases. Especially EVB19 is very important in the pathogenesis of autoimmune thyroid diseases. Thus in some case presentations; it was shown that EVB19 might be related with Hashimoto’s thyroiditis. Although etiopathogenesis of Graves’ disease and Hashimoto’s thyroiditis is not known exactly; they are thought to occ...

Self-monitoring of blood glucose (SMBG) increases life expectancy and improves diabetic patients’ quality of life. 17 type 1 diabetic patients and 159 type 2 diabetic patients’ files were randomly evaluated to evaluate SMBG practice patterns in our hospital. All type 1 patients used insulin, while 38 type 2 diabetic patients used drug only, 35 type 2 diabetic patients used drugs in combination with insulin and 86 type 2 diabetic patients used insulin only. 90.3% of o...

A 41 year old male patient presented to the endocrinology unit due to recurrent long bone fractures and teeth decay. His past medical history was nonsignificant for any chronic disease. He was a child of consanguineous marriage; his father and mother were first degree cousins. There were no other family members with similar phenotype or history of recurrent fractures He was 154 cm in height and weighed 58 kg. The arm span was 139 cm. Upper to lower segment ratio was 1.16. He h...

A 27 year-old-man was admitted to our hospital with pain in the back. Bone mineral density evaluation revealed severe osteoporosis at L1–L4 vertebrae, as well as on femur, too. Secondary osteoporosis reasons like thyrotoxicosis, glucocorticoid therapy, hypercortisolemia, hypercalciuria, hyperparathyroidism were excluded. Laboratory examination of the patient revealed to a hypoglobulinemia. Further evaluation of the immunoglobulin levels were in concordance with panhypoglo...

Introduction: Subacute thyroiditis (SAT) is a self-limiting thyroid disease associated with a triphasic clinical course of hyperthyroidism, hypothyroidism, and return to normal thyroid function. The well-known clinical features of SAT include thyroid pain with symptoms of hyperthyroidism, suppressed level of thyroid-stimulating hormone (TSH), low thyroid uptake of radioactive iodine, and elevated erythrocyte sedimentation rate. Diagnosis is based on clinical and laboratory dat...

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

Thyroid cancer is the most common cancer in the endocrine system. Thyroid follicular epithelial-derived cancers are papillary, follicular, and anaplastic cancer. Risk factors for differentiated cancers are radiation exposure, and family history. Possible risk factors like occupational and environmental exposures, increased parity, late age at first pregnancy, and hepatitis C-related chronic hepatitis are potential but not proven risk factors. In order to evaluate other potenti...