ea0056gp141 | Neuroendocrinology | ECE2018
Barroso Alexia
, Franssen Delphine
, Ruiz-Pino Francisco
, Vazquez Maria Jesus
, Garcia-Galiano David
, Castellano Juan Manuel
, Onieva Rocio
, Rodriguez Ana Belen
, Gaytan Francisco
, Dieguez Carlos
, Pinilla Leonor
, Lopez Miguel
, Roa Juan
, Tena-Sempere Manuel
GnRH neurons are the final output of the brain controlling reproduction. These neurons receive information from multiple central and peripheral signals, ranging from gonadal steroids to metabolic cues and brain neuropeptides, to regulate their activity. AMP-activated protein kinase (AMPK) is an intracellular sensor, activated by energy deficiency, involved in the regulation of the cellular and whole-body energy homeostasis. Previous in vitro studies suggested the part...