Searchable abstracts of presentations at key conferences in endocrinology

ea0022p561 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

The diagnosis of GH deficiency in obese patients: what help from pharmacological blockade of lipolysis?

Orsini Federica , Cattaneo Agnese , Grasso Alice , Filippini Barbara , Fatti Maria Letizia , Moro Mirella , Scacchi Massimo , Cavagnini Francesco

The diagnostic approach to GH deficiency (GHD) in obese patients is complicated by the reduced spontaneous and stimulated GH secretion associated with overweight. A GH response to GHRH+arginine lower than 4.2 μg/l is currently considered indicative of GHD in obesity (Corneli et al., Eur J Endocrinol 2005). Aim of the study was to verify the diagnostic validity of this cut-off value by investigating the effect of acute pharmacological blockade of lipolysis on...