Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp259 | Thyroid non cancer - Autoimmune Thyroid disease/pregnancy | ECE2018

Thyroid disorders in patients with advanced neoplastic disease treated with immune checkpoints inhibitors

Fidilio Enzamaria , Velasquez Mayra A , Sanz Eva , Ortiz Angel M , Ciudin Andreea , Mesa Jorge , Zafon Carlos

The use of immune checkpoint inhibitors (ICPI) for treatment of different advanced cancers has opened a new therapeutic window. Thyroid dysfunction is an often side effect described for these drugs.Objectives: To describe the thyroid alterations found in oncologic patients undergoing treatment with ICPI.Materials and methods: A descriptive, retrospective study of oncologic patients receiving treatment with ICPI referred to the Endo...

ea0090p276 | Adrenal and Cardiovascular Endocrinology | ECE2023

The impact of Bariatric Surgery on the 1mg Dexamethasone Suppression Test in patients with Severe Obesity

Casteras Anna , Fidilio Enzamaria , Comas Marta , Michael Ortiz Angel , Biagetti Betina , Zabalegui Alba , Filippi Francesca , Giralt Marina , Ferrer Roser , Vilallonga Ramon , Ciudin Andreea

Background: The cortisol suppression test with 1 mg dexamethasone (DST) is a screening test for hypercortisolism with high sensitivity (95%) for serum cortisol cut-off <1.8 μg/dl. However, cortisol tests may give false positive in patients with severe obesity (SO). On the other hand, bariatric surgery (BS) is the most effective treatment for SO, and the operated population is growing. At present there is no reliable data regarding the impact of BS on DST results in pa...

ea0041ep262 | Clinical case reports - Pituitary/Adrenal | ECE2016

Left adrenal Ectopic cushing syndrome even more challenging

Biagetti Betina , Simo Olga , Ortiz Angel , Iglesias Carmela , Dalama Belen , Obiols Gabriel , Castell-Conesa Joan , Gracia-Burillo Amparo , Caubet Enric , Mesa Jordi

Background: The Ectopic ACTH Syndromes (EAS) often associated with severe hypercortisolism are really a challenge.Case presentation: We report the case of a 48-year-old woman, newly diagnosed with hypertension, hypokalemia despite renin-angiotensin blockers intake, and complaints of intense fatigue, muscular weakness, and easy bruising, which worse in four months. EAS was biochemically confirmed, but two urinary catecholamines collection were negatives d...

ea0056gp153 | Obesity | ECE2018

How to better predict weight loss and type 2 diabetes remission after bariatric surgery? the potential role of genetic scoring systems in clinical practice

Lecube Albert , Simo Rafael , Ciudin Andreea , Pich Sara , Vilarrasa Nuria , Caixas Assumpta , Sanchez Enric , Simo Andreu , Gutierrez Liliana , Salas Eduardo , Ortega Israel , Guillen Kevin , Casagran Oriol , Rigla Mercedes , Baena Juan Antonio , Fort Jose Manuel , Luna Alexis , Rebasa Pere , Balibrea Jose Maria , Fidilio Enzamaria , Bueno Marta , Pareja Rocio , Hurtado Marta , Ortiz Angel , Hernandez Cristina

Introduction: Obesity and its comorbidities, specially type 2 diabetes (T2D), are a major public health problem. The disappointing result of dietary treatment and the scarce of drugs have led to increased bariatric surgery (BS) as the most efficient therapeutic option. However, not all obese patients with T2D who undergo BS achieve diabetes remission.Objective: To develop a genetic scoring system for predicting T2D remission following BS. 2) To compare o...