Searchable abstracts of presentations at key conferences in endocrinology

ea0056p818 | Pituitary - Clinical | ECE2018

Diabetes insipidus due to hypothalamitis and infundibulo-neurohypophysitis

Oruk G Gonca , Apaydin Melda

Autoimmune hypothalamitis has been implicated in idiopathic central diabetes insipidus (DI) due to antibodies against vasopressin producing hypothalamic cells. Lymphocytic infiltration of hypothalamus has been reported in patients with lymphocytic hypophysitis (LH) manifesting as hypopituitarism with DI. These patients can also have other associated autoimmune diseases. Here, we report a case of a male patient who presented with headache, poor orientation, partial hypopituitar...

ea0049ep964 | Pituitary - Clinical | ECE2017

Pregnancy in Cushing’s disease after treatment with surgery and cyber-knife radiosurgery

Oruk G Gonca , Olmezoglu Ali , Apaydin Melda , Guvenc Gonul

Women affected by Cushing’s disease (CD) are often infertile due to abnormal follicular development or anovulation. In these patients, first line treatment is pituitary surgery, which is effective in more than 83% of cases with microadenomas, but only in about 35% of those with macroadenomas. When surgery do not normalize circulating ACTH and cortisol concentrations, such drugs, e.g. ketoconazole or metirapone, and radiotherapy are used as adjuvant treatment. Concerning r...

ea0037ep715 | Pituitary: clinical | ECE2015

Evaluation of thyroid nodules in acromegaly

Oruk G Gonca , Koruyucu Melike Bedel , Yilmaz Husnu , Pamuk Baris

Nodular thyroid disease is frequently observed in patients with acromegaly. The aim of this study is to evaluate thyroid nodules and thyroid cancer frequency in acromegalic patients. The data of 125 acromegalic (55 males and 70 females) patients followed over 10 years were evaluated retrospectively from the recorded files. Data for gender, age, duration of acromegaly, thyroid function tests, thyroid ultrasonography (US), and thyroid fine needle aspiration biopsy (FNAB) and thy...

ea0056p824 | Pituitary - Clinical | ECE2018

Hypothalamic involvement in diffuse large B-celllymphoma

Apaydin Melda , Oruk G Gonca , Rezanko Turkan Atasever , Yilmaz Asu Fergun

Non-hodgkin lymphoma (NHL) is a hematological tumor caused by abnormal lymphoid proliferation. NHL can arise in any part of the body, including central nervous system (CNS). However, hypothalamus involvement is a rare presentation. Here, we report a case of hypothalamic infiltration of NHL Diffuse Large B-cell lymphoma (DLBCL) in a 21 years old male patient with panhypopituitarism and diabetes insipidus. The patient was admitted to the hospital with a history of nausea, vomiti...

ea0037ep1254 | Clinical Cases–Thyroid/Other | ECE2015

A rare case of triple parathyroid adenoma with hyperparathyroidism occurring at a young age

Oruk G Gonca , Haciyanli Mehmet , Koruyucu Melike Bedel , Ruksen Ebru , Gur Ozlem , Tavusbay Cengiz , Yilmaz Husnu , Pamuk Baris

Lesions causing primary hyperparathyroidism (PHP) can be summarised as solitary adenoma (80–85%), multiglandular hyperplasia (15%), parathyroid carcinoma (1%). While double adenomas are identified in 2–15% of the patients which are operated for PHP, triple adenomas are very rare. The case is presented because in the recent years patients who are admitted to the hospital with intense bone complaints are very unusual and multiple adenomas are also seldom. 22 years old ...