Searchable abstracts of presentations at key conferences in endocrinology

ea0016p694 | Thyroid | ECE2008

Cyclin A and B1 are overexpressed in thyroid cancers which had been operated for indeterminate, nondiagnostic, or suspicious fine-needle aspirate results

Demirer Asli Nar , Ozen Ozlem , Sengul Aysegul , Tutuncu Neslihan Bascil , Gursoy Alptekin , Demirag Nilgun Guvener

Objective: Approximately 30% of patients with thyroid nodules have indeterminate, nondiagnostic, or suspicious fine-needle aspiration (FNA) biopsy results. These patients usually undergo thyroidectomy because of cancer risk. Our aim was to determine diagnostic markers to distinguish benign from malignant thyroid neoplasms, so we focused on G2-M boundary regulators of the cell cycle and investigated the expression of two proteins, cyclin A and cyclin B1.M...