Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep770 | Pituitary and Neuroendocrinology | ECE2020

Massive pulmonary embolism in a newly diagnosed acromegaly patient

Hepsen Sema , Ucan Bekir , Akhanli Pinar , Ozturk Unsal Ilknur , Cakal Erman

Introduction: Acromegaly is caused by growth hormone (GH) and insulin-like growth factor (IGF-1) excess and leads to various comorbidities. However, the association between acromegaly and thromboembolic diseases is unclear. Herein, we present a newly diagnosed acromegaly patient with massive pulmonary embolism.Case report: A 61-year-old female was hospitalized with acromegaly pre-diagnosis. She complained about extensive arthralgia and snoring. She had h...

ea0070ep548 | Hot topics (including COVID-19) | ECE2020

Teriparatide treatment in a patient with resistance hypoparathyroidism

Erkam Sencar Muhammed , Calapkulu Murat , Ozturk Unsal İlknur , Hepsen Sema , Ozbek Mustafa , Cakal Erman

Background: Hypoparathyroidism is an uncommon disorder of calcium metabolism characterized by hypocalcemia, hyperphosphatemia, and reduced level of parathyroid hormone (PTH). The most common cause of hypoparathyroidism is accidental damage to the parathyroid glands during thyroid surgery. There are no formal guidelines for hypoparathyroidism management. The main goal of treatment is to improve the symptoms of hypocalcemia, to keep the serum calcium within the low normal range,...

ea0070aep33 | Adrenal and Cardiovascular Endocrinology | ECE2020

Adrenocortical cancer mimicking lymphoma on magnetic resonance scan

Calapkulu Murat , Erkam Sencar Muhammed , Duger Hakan , Kizilgul Muhammed , Ucan Bekir , Ozturk Unsal İlknur , Akhanli Pinar , Cakal Erman

Background: Adrenocortical carcinoma (ACC) is a rare cancer that originates from the cortex of the adrenal gland. Although its exact etiology is not clear, it has been found to be associated with some hereditary cancer syndromes. Sometimes patients present with hormonal excess symptoms (virilization, Cushing’s syndrome) or local symptoms consistent with an abdominal mass. In ACC, computed tomography (CT) and magnetic resonance imaging (MRI) are preferred imaging modaliti...

ea0070aep601 | Pituitary and Neuroendocrinology | ECE2020

A case of wolfram syndrome with primary hypogonadism

Calapkulu Murat , Erkam Sencar Muhammed , Ozturk Unsal İlknur , Duger Hakan , Kizilgul Muhammed , Bostan Hayri , Cakal Erman , Ozbek Mustafa

Introduction: Wolfram syndrome, is a rare autosomal recessive genetic disorder that is characterized by diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy, and sensorineural deafness as well as various other possible disorders. DM is the first manifestation, and optic atrophy also onsets in the first decade of life. The onsets of DI and sensorineural deafness are in the second decade, urinary tract abnormalities are in the third decade, and neurologic abnormalities...

ea0029p1662 | Thyroid (non-cancer) | ICEECE2012

Elastography in the differential diagnosis of thyroid nodules

Cakal E. , Sahin M. , Ozturk Unsal I. , Gungunes A. , Tutal Akkaymak E. , Cakir Ozkaya E. , Colak Bozkurt N. , Ozbek M. , Delibasi T.

Objective: Despite the publication of a recent meta-analysis of elastography in thyroid nodules, further work is necessary on this issue in different populations. In this study we aimed to evaluate the clinical value of elastography in nodular goiter in mild iodine defficient region without excluding according to nodule charecteristics.Materials and methods: This prospective study was conducted between April 2010 and December 2011 in Yildirim Beyazit Dis...

ea0029p1444 | Pituitary Clinical | ICEECE2012

Evaluation of cardiovascular risk factors and metabolic profile in hyperprolactinemic subjects

Sayki Arslan M. , Sahin M. , Esra T. , Cakir Ozkaya E. , Bozkurt Colak N. , Karbek B. , Ozturk Unsal I. , Ucan B. , Gungunes A. , Cakal E. , Ozbek M. , Topaloglu O. , Demirci T. , Karakose M. , Caliskan M. , Ginis Z. , Delibasi T.

Objective: Hyperprolactinemia has been reported to be associated with abnormalities of glucose metabolism and cardiovascular inflammatory markers. However, the metabolic effects of high prolactin levels are not adequately clarified. The aims of this study were to evaluate the effects of hyperprolactinemia on endothelial function, insulin sensitivity and inflammatory markers in prolactinoma diagnosed subjects.Methods: In total, 58 hyperprolactinemic subje...

ea0029p1725 | Thyroid (non-cancer) | ICEECE2012

Serum nesfatin-1 levels in overt and subclinical hyperthyroidism

Gungunes A. , Ginis Z. , Demirci T. , Cakir E. , Karbek B. , Sayki Arslan M. , Ozturk Unsal I. , Tutal Akkaya E. , Ucan B. , Cakal E. , Gultuna Ozguclu S. , Ozbek M. , Sahin M. , Topaloglu O. , Delibasi T.

Objective: Nesfatin-1, was recently discovered in the brain which is derived from nucleobindin2 (NUCB2). Central and peripheral administration of nesfatin-1, inhibits food intake, dose-dependently. Hyperthyroid patients have increased appetite and food intake with a craving for carbohydrate-rich food, at the beginning of disease, but the physiological mechanisms underlying this behavior is not known exactly. In this study, we investigated whether nesfatin-1 is involved in the ...