Searchable abstracts of presentations at key conferences in endocrinology

ea0081p519 | Adrenal and Cardiovascular Endocrinology | ECE2022

Brain Structure in a cohort of young adult patients with Autoimmune Addison’s Disease

van't Westeinde Annelies , Padilla Nelly , Strom Sara , Kampe Olle , Bensing Sophie , Lajic Svetlana

Background: Both cortisol and other adrenal hormones are well known to affect brain structure and function throughout development. Due to destruction of the adrenal cortex, patients with Autoimmune AddisonÂ’s disease (AAD) lack production of adrenal hormones and therefore receive lifelong replacement of cortisol and aldosterone, and, for some female patients dehydroepiandrosterone (DHEA). However, replicating the natural rhythm of secretion is difficult, and patients are o...