Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep775 | Pituitary: clinical | ECE2015

Congenital pituitary stalk interruption syndrome with isolated GH and TSH deficiency and Rathke's cleft cyst: an incidental association

Wessling Ana , Paixao Raquel , Aragues Jose Maria , Mascarenhas Mario

Introduction: Congenital pituitary stalk interruption syndrome (PSIS) is a rare condition, characterized by the triad (not always complete): absence/hypoplasia of the pituitary stalk, hypoplasia/aplasia of the anterior pituitary and absence or ectopy of the posterior pituitary high signal intensity, on magnetic resonance imaging (MRI). PSIS implies a permanent GH deficiency, in 77% associated with other pituitary hormones deficiencies. The aetiology remains uncertain, but some...

ea0041ep141 | Calcium and Vitamin D metabolism | ECE2016

Idiopathic infantile hypercalcemia: presenting in childhood, diagnosed in adulthood – case report

Silvestre Catarina , Paixao Raquel , Aragues Jose Maria , Guerra Silvia , Mascarenhas Mario

Introduction: Hypercalcemia can be caused by a variety of pathologies/factors. Vitamin D plays a central role in calcium homeostasis, where a tight control of its metabolism is necessary. Inadequate 24-hydroxylase-enzime (CYP24A1) activity leads to failure of 25-hydroxyvitamin and 1,25-dihydroxy-vitamin D3 inactivation, resulting in hypercalcemia.Case report: An asymptomatic, 22-year-old woman was admitted in an Endocrinology appointment for evaluation o...

ea0049ep243 | Bone & Osteoporosis | ECE2017

Impact of vitamin D on the bone quality assessed by trabecular bone score in men

Mascarenhas Mario Rui , Barbosa Ana Paula , Duarte Nuno , Wessling Ana , Gomes Ana Raquel Coelho , Faria Carolina , Paixao Raquel , Barbosa David , Silvestre Catarina , Poupino Jose , Gomes Vania , Osorio Ana Sofia , Sampaio Francisco , Monteiro Jacinto , Hans Didier , Bicho Manuel , Bugalho Maria Joao

Trabecular bone score (TBS) is a recent noninvasive analytical method, based upon DXA images, related to bone microarchitecture or bone quality; together, TBS and DXA may evidence bone strength. Falls and osteoporotic fractures increase with ageing, while both BMD and vitamin D levels slowly decline. Data about the influence of vitamin D on the TBS are scarce.Aim: To evaluate the influence of the blood vitamin D levels on the TBS in normal men.<p cla...

ea0049ep1083 | Bone &amp; Osteoporosis | ECE2017

Effects of male hypogonadism treatment on the bone mineral density

Mascarenhas Mario Rui , Barbosa Ana Paula , Gomes Ana Raquel Coelho , Silvestre Catarina , Barbosa David , Paixao Raquel , Faria Carolina , Osorio Ana Sofia , Gomes Vania , Ferreira Joana , Bicho Manuel , Bugalho Maria Joao

Increased recognition of the morbidity and mortality due to osteoporosis in men are main issues of public health. Ageing and the propensity to falls are the main risk factors for osteoporotic fractures in men; moreover, hypogonadism is an important secondary cause of low bone mineral density (BMD), but very little is known about the effect of hypogonadism treatment on the BMD.Objective: The aim was to study the impact on BMD of the treatment of male hypo...