Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep276 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Heterozygous familial hypercholesterolemia with intolerance to PCSK9 inhibitors

Saraiva Miguel , Palma Pedro , José Alexandre Queirós , Palma Isabel

IntroductionHeterozygous familial hypercholesterolemia is one of the most common genetic disorders and it is associated with an at least ten times higher risk of coronary heart disease. Frequently, it is necessary to medicate the patients with PCSK9 inhibitors (PCSK9i) so they can reach LDL-c target values. In Portugal, the only evolocumab is available and the most commonly reported adverse effects are local pruritus and upper airway symptoms.<p clas...

ea0014p45 | (1) | ECE2007

Progression of diabetic retinopathy in pregestational diabetes mellitus

Guerrero R , Martinez Brocca MA , Pomares MA , Palma S , Gonzalez I , Acosta D , Moreno E , Villamil F

Background: Pregnancy may adversely affect the progression of diabetic retinopathy and can have serious implications for the pregnant women.Aim: To asses the impact of pregnancy on the progression of diabetic retinopathy in women with type 1 and type 2 diabetes mellitus and to identify risk factors for the progression of retinopathy during pregnancy.Methods: 306 diabetic women, 229 (75.4%) with type 1 and 77 (23.9%) with type 2 di...