Searchable abstracts of presentations at key conferences in endocrinology

ea0044p83 | Clinical biochemistry | SFEBES2016

Audit on isolated pituitary stalk lesions/thickening in a tertiary hospital: Comprehensive guidelines needed

Jolly Karan , Cooke Hannah , Smith William , Tampourlou Metaxia , Ayuk John , Paluzzi Alessandro , Ahmed Shahzada , Karavitaki Niki

Background: Isolated pituitary stalk (PS) lesions/thickening detected on imaging pose challenging dilemmas.Aim: Audit the diagnostic approach and management of patients with isolated PS lesions/thickening reported on MRI in a tertiary hospital.Methods: Reports of pituitary/brain MRIs performed in our Radiology Department between 1/2013 and 12/2015 were searched for the terms ‘stalk’, ‘infundibular’, ‘infund...

ea0065p292 | Neuroendocrinology | SFEBES2019

Cabergoline in the treatment of acromegaly: experience from a large pituitary centre

Samperi Irene , Lithgow Kirstie , Chai Shu Teng , Asia Miriam , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Meade Sara , Sanghera Paul , Toogood Andy , Gittoes Neil , Ayuk John , Karavitaki Niki

Introduction: Cabergoline is one of the medical treatments in acromegaly; it can be used alone or in combination with other available agents.Aim: To review the efficacy of cabergoline in patients with acromegaly treated in our centre.Patients and methods: Patients with acromegaly on cabergoline were identified from our Pituitary Registry. Clinical/laboratory/imaging data were collected and analysed.Results: F...

ea0065p284 | Neuroendocrinology | SFEBES2019

Silent somatotroph pituitary neuroendocrine tumours (PitNETs): systematic review of cases from a Pituitary Centre

Nazir Muneer Ahmad Abdul , Fountas Athanasios , Lithgow Kirstie , Ayuk John , Toogood Andy , Gittoes Neil , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Nagaraju Santhosh , Pohl Ute , Karavitaki Niki

Introduction: Silent somatotroph Pituitary Neuroendocrine Tumours (PitNETs) are extremely rare (2−3% of surgically treated pituitary tumours) and data on their natural history and outcomes are scarce.Aim: To review systematically the cases of these tumours presenting in our Centre.Patients and methods: Patients with this diagnosis were identified from our Pituitary Registry and clinical/laboratory/imaging data were collected ...

ea0065p315 | Neuroendocrinology | SFEBES2019

The spectrum of testosterone levels in males with functioning gonadotroph adenomas: report of three cases

Fountas Athanasios , Samperi Irene , Webster Rachel , Asia Miriam , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ayuk John , Toogood Andy , Gittoes Neil , Karavitaki Niki

Introduction: Functioning gonadotroph adenomas (FGAs) are very rare tumours secreting biologically active gonadotropins. In males, typically, FSH levels are elevated, whereas LH and testosterone are variable. Herein, we present three males with elevated, normal or low testosterone at diagnosis.Cases: Case 1:42-year-old man with two-year history of visual impairment. Bitemporal hemianopia was confirmed. Imaging showed macroadenoma compressing optic chiasm...

ea0049gp180 | Pituitary | ECE2017

Outcome of non-functioning pituitary adenomas that regrow after primary treatment: a study from two large specialist UK centers

Tampourlou Metaxia , Ntali Georgia , Ahmed Shahzada , Arlt Wiebke , Ayuk John , Byrne James , Chavda Swarupsinh , Cudlip Simon , Gittoes Neil , Grossman Ashley , Mitchell Rosalind , O'Reilly Michael , Paluzzi Alessandro , Toogood Andrew , Wass John , Karavitaki Niki

Introduction: Despite the significant risk of regrowth of non-functioning pituitary adenomas (NFAs) after primary treatment, systematic data on the probability of further tumour progression and the effectiveness of management approaches are lacking.Aims: Assess the probability of further regrowth(s), predictive factors and outcomes of management approaches in patients with NFA diagnosed with adenoma regrowth after primary treatment (surgery combined or n...