Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep523 | Pituitary and Neuroendocrinology | ECE2021

Biliary ultrasound surveillance in patients with acromegaly treated with somatostatin receptor ligands: A large tertiary centre experience

Panagiotou Grigorios , Mamoojee Yaasir , James Andy

BackgroundSomatostatin receptor ligands (SRL) are commonly used in patients with acromegaly to control insulin growth factor 1 (IGF1) concentrations. Biliary sludge or gallstone formation are well-recognised biliary adverse events (BAE) from SRL therapy. Our current practice is to routinely monitor patients with acromegaly on SRL with ultrasound scanning (USS). Once BAE are detected, ursodeoxycholic acid (UDCA) therapy is initiated.<p class="abstext"...

ea0077p218 | Neuroendocrinology and Pituitary | SFEBES2021

Imaging screening for lung cancer required at diagnosis and at 6 months after established diagnosis of SIADH? A retrospective Audit of real-life clinical practice

Ahmad Waqar , Ahmed Sajeel , Panagiotou Grigorios , Pearce Simon

Background: Syndrome of Inappropriate Anti-diuretic Hormone (SIADH) secretion is the most common cause of hyponatremia in cancer patients. About 14% of hyponatremia in medical inpatients is due to underlying tumor-related conditions. We performed an audit to evaluate prevalence of lung malignancy in patients newly diagnosed with SIADH and to assess proportion of patients having radiological evidence of lung cancer through chest x ray and/or CT chest imaging six months after es...

ea0086oc4.1 | Adrenal and Cardiovascular | SFEBES2022

Introducing technology to improve patient safety in adrenal insufficiency: a proof-of-concept delivery of a new smartphone app in steroid-dependent patients

Panagiotou Grigorios , Lewis Janet , Sall Seetal , Lansdown Andrew

Introduction: Although significant developments have been achieved in the management of steroid-dependent patients, little progress has been made in ensuring their safety using smartphone technology. We present the use of a novel app in steroid-dependent patients.Methods: A group of unselected individuals currently on steroid replacement due to adrenal insufficiency (AI) were assessed regarding their access to intramuscular (IM) hydrocortisone. A smartph...

ea0041ep785 | Obesity | ECE2016

Interventional changes of thyroid hormone levels do not affect circulating irisin levels in humans

Panagiotou Grigorios , Pazaitou-Panayiotou Kalliopi , Komninou Despina , Paschou Stavroula A. , Kalogeris Nikolaos , Vryonidou Andromachi , Mantzoros Christos S.

Introduction: Thyroid hormones and irisin increase energy expenditure and induce browning of adipose tissue. However, little is known about irisin physiology and regulation. Here we aim to elucidate whether thyroid hormones alter circulating irisin concentrations in humans.Design and subjects: One cross-sectional (case-control) evaluation and two interventions were performed independently from each other, including previously thyroidectomized patients. C...

ea0056p232 | Calcium &amp; Vitamin D metabolism | ECE2018

Preoperative serumvitamin D levels in patients with breast cancer: association with histological characteristics

Panagiotou Grigorios , Komninou Despina , Triantafillidou Sofia , Vagionas Anastasios , Pazaitou-Panayiotou Kalliopi , Tsakalof Andreas

Objective: Vitamin D is a multifunctional hormone with possible antitumor effects. Its exact role in breast carcinogenesis remains largely unknown. We evaluated serum vitamin D levels in female patients with recently identified benign or malignant lesions of the breast and its associations with tumor histology.Subjects-methods: One hundred sixty women with suspicious breast masses that required surgical excision were included in this study. Body composit...

ea0070oc6.6 | Hot Topics (including COVID-19 | ECE2020

Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalised with COVID-19 are associated with greater disease severity

Tee Su , Panagiotou Grigorios , Ihsan Yasir , Athar Waseem , Marchitelli Gabriella , Kelly Donna , Boot Christopher S , Stock Nadia , Macfarlane James , Martineau Adrian , Burns Graham , Quinton Richard

Background: The pandemic of Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is associated with higher fatality in respect of male sex, advancing age, obesity, diabetes, hypertension, climatic factors and, in the UK and North America, with darker-skinned ethnicities; in all of which circumstances vitamin D deficiency (VDD) is more common. 25(OH)D levels reach their nadir at the end of winter and have been associated wit...