Searchable abstracts of presentations at key conferences in endocrinology

ea0059cmw4.1 | Workshop 4: Treating troublesome menopausal symptoms | SFEBES2018

HRT: Efficacy and Safety

Panay Nick

The adverse outcomes seen in The Women’s Health Initiative (WHI) combined hormone therapy trial were mainly due to an over-dosage of hormone therapy (HT) in a relatively elderly population. However, fundemental differences exist between conjugated equine estrogens and 17 beta estradiol and between medroxyprogesterone acetate and other progestogens. It is likely that these differences also contributed to the adverse outcomes in WHI, which were contrary to the cardiovascula...

ea0034p332 | Reproduction | SFEBES2014

Regulation of the LH/CG receptor signalling in human endometrium

West Camilla , Hanyaloglu Aylin , Brosens Jan , Lavery Stuart , Panay Nick

It is well established that the interaction between an implanting embryo and the endometrium is essential for successful implantation and there is a variety of locally secreted factors within the uterine environment which underlies this maternal–fetal cross-talk. Human chorionic gonadotrophin (hCG) is a glycoprotein hormone secreted by the embryo and is essential during early stages of pregnancy to maintain progesterone production from the corpus luteum. Its receptor (LH/...

ea0086p126 | Reproductive Endocrinology | SFEBES2022

Experience of Prescribing Testosterone Gel to Menopausal Women at a Single UK Centre: The Biochemistry and The Patent Experience

Heald Adrian , Naseem Asma , Keatley Claire , Duran Beatriz , Cortes Moreno Gabriela , Panay Nick

Introduction: It has been suggested that sexual dysfunction affects as many as 43% of women in the population. In relation to this, symptoms of hypoactive sexual desire disorder (HSDD) can be alleviated with testosterone replacement.Aim: To determine what is the pre- and 24-hour post dose circulating level of testosterone in women applying Testogel 16.2 mg/g.Methods: In a group of 10 menopausal women applying Testogel 16.2 mg/g at ...

ea0094p116 | Reproductive Endocrinology | SFEBES2023

Patient and healthcare providers experience of access to menopause-related information and menopause-care provision across the UK: Results from a nationwide survey

Koysombat Kanyada , Pedder Hugo , Vinogradova Yana , Qayum Ambreen , N Comninos Alexander , Talaulikar Vikram , Panay Nick , S Dhillo Waljit , Mukherjee Annice , Abbara Ali

Menopause management guidelines advocate a personalised, evidence-based approach to menopause-care. This study explored the current landscape of menopause-care, from both patients’ and healthcare-providers’ perspectives, to better understand barriers to menopause-care across the UK.Methods: A 25-question online patient-survey and a 23-question GP-survey was designed with individuals with lived-experience of menopause to underst...