Searchable abstracts of presentations at key conferences in endocrinology

ea0014oc11.5 | Reproductive endocrinology II | ECE2007

Integration of the EGF network with early LH signal in preovulatory follicles

Panigone Sara , Hsieh Minnie , Persani Luca , Conti Marco

Recent studies demonstrate an essential role of the EGF network in propagating the LH signal within ovarian preovulatory follicles. However, the molecular bases for the integration are poorly characterized. Here, we propose that the early LH signal leading to ovulation is amplified through activation of the EGF network.For this study, preovulatory follicles from euthanized gonadotropin-primed mice were isolated and cultured with or without recombinant LH...