Endocrine Abstracts

Objective: To assess the impact of genetic polymorphisms associated with increased cardiovascular risk on the lipid profile in healthy postmenopausal women.Methods: The study population consisted of 84 women between 49–69 years who had been menopausal for at least one year. The genetic polymorphisms examined were the following: Glycoprotein IIIa leu33pro, Apolipoprotein E2/E3/E4, Methylenotetrahydrofolate reductase ala222val, Apolipoprotein B arg350...

Objective: To assess the interrelation of the MTHFR ala222val polymorphism, correlated with increased rates of cardiovascular disease, with indices of androgenicity in healthy postmenopausal women.Methods: The population of this cross-sectional study consisted of 84 healthy women who had been menopausal for at least one year. The examined polymorphism was Methylenetetrahydrofolate reductase ala222val, while the hormonal assays included Testosterone, Sex ...

Objective: To investigate the effect of BMI on the absolute change from baseline levels in circulating sex hormone in postmenopausal women treated with oral continuous combined low dose HT for 6 months.Design: The study recruited 36 postmenopausal women who received daily E2 1 mg/NETA 0.5 mg for 6 months. Hormonal assessment included measures of serum concentrations of FSH, LH, 17β-estradiol and free estrogen index (FEI), total and free testosterone...