Searchable abstracts of presentations at key conferences in endocrinology

ea0026p586 | Clinical case reports | ECE2011

A case report of macronodular adrenal hyperplasia with combined cortisol and aldosterone oversecretion in response to β-adrenergic and vasopressin stimuli

Papanastasiou L , Pappa T , Tsiavos V , Tseniklidi E , Prevoli A , Tsounas P , Markou A , Piaditis G

Introduction: Adrenocorticotropin (ACTH)-independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of CushingÂ’s syndrome, commonly involving the aberrant expression of several membrane-bound adrenal receptors. Recent studies have investigated whether the latter is also implicated in the renin-independent aldosterone secretion of hyperaldosteronism cases.Case report: A 35-year-old man presented to our department for evaluation of new-onset...

ea0029p12 | Adrenal cortex | ICEECE2012

Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension

Pappa T. , Papanastasiou L. , Kaltsas G. , Markou A. , Tsounas P. , Tsiavos V. , Dasou A. , Tsiama V. , Zografos G. , Piaditis G.

Introduction: Autonomous aldosterone secretion (AAS) is present in approximately 10% of hypertensives. Adrenal incidentalomas (AI) can be found in up to 19% of hypertensive individuals. However, data on the incidence of AAS in hypertensive patients with AI is scarce. Our aim was to evaluate the adrenal aldosterone secretory profile in patients with adrenal adenomas with and without arterial hypertension.Patients and methods: We investigated 72 normotensi...

ea0029p58 | Adrenal cortex | ICEECE2012

Treatment with mineralocorticoid receptor antagonists in ‘subclinical’ cases with adrenal adenomas and autonomous aldosterone secretion

Papanastasiou L. , Pappa T. , Tsounas P. , Tsiavos V. , Markou A. , Tseniklidi E. , Anastasakou M. , Fountoulakis S. , Prevoli A. , Piaditis G.

Introduction: Patients with adrenal adenomas appear to exhibit an appreciable prevalence of autonomous aldosterone secretion (AAS). Our aim was to evaluate the anti-hypertensive effect of targeted therapy with mineralocorticoid receptor (MR) antagonists in AAS patients.Patients and methods: We studied 60 hypertensive patients, 21 males and 39 females, harboring an adrenal adenoma with AAS. All patients were receiving combination of anti-hypertensive trea...